7601 - 7650 of 8471 Results
Title
Year
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OPENTitle: Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 12Start Page: e85443End Page: e85443Publication Date:Open Access(OA) Status: OPENLicense: cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0085443Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0085443&type=printableCitation Count: 18
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OPENTitle: Human A53T α-Synuclein Causes Reversible Deficits in Mitochondrial Function and Dynamics in Primary Mouse Cortical NeuronsJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 12Start Page: e85815End Page: e85815Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0085815Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0085815&type=printableCitation Count: 60
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OPENTitle: Pedunculopontine Nucleus Area Oscillations during Stance, Stepping and Freezing in Parkinson’s DiseaseJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 12Start Page: e83919End Page: e83919Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0083919Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0083919&type=printableCitation Count: 74
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OPENTitle: A noninvasive handheld assistive device to accommodate essential tremor: A pilot studyJournal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 6Start Page: 838End Page: 842Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25796Best OA location URL: https://europepmc.org/articles/pmc4156033?pdf=renderCitation Count: 50
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OPENTitle: Expression of peroxisome proliferator-activated receptor-gamma in the substantia nigra of hemiparkinsonian nonhuman primatesJournal Name: Neurological ResearchPublisher: Informa UK LimitedVol: 36Issue #: 7Start Page: 634End Page: 646Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1179/1743132813y.0000000305Best OA location URL: https://europepmc.org/articles/pmc4254814?pdf=renderCitation Count: 27
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OPENTitle: Results of the citalopram to enhance cognition in Huntington disease trialJournal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 3Start Page: 401End Page: 405Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25750Best OA location URL: https://europepmc.org/articles/pmc3960314?pdf=renderCitation Count: 59
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RESTRICTEDTitle: The microtubule associated protein tau H1 haplotype and risk of essential tremorJournal Name: European Journal of NeurologyPublisher: WileyVol: 21Issue #: 7Start Page: 1044End Page: 1048Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/ene.12335Best OA location URL: https://europepmc.org/articles/pmc4057305?pdf=renderCitation Count: 12
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OPENTitle: Oxidation-induced Structural Changes of Ceruloplasmin Foster NGR Motif Deamidation That Promotes Integrin Binding and SignalingJournal Name: Journal of Biological ChemistryPublisher: Elsevier BVVol: 289Issue #: 6Start Page: 3736End Page: 3748Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1074/jbc.m113.520981Best OA location URL: http://www.jbc.org/article/S0021925819747607/pdfCitation Count: 34
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OPENTitle: Continuous intrajejunal infusion of levodopa-carbidopa intestinal gel for patients with advanced Parkinson's disease: a randomised, controlled, double-blind, double-dummy studyJournal Name: The Lancet NeurologyPublisher: Elsevier BVVol: 13Issue #: 2Start Page: 141End Page: 149Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/s1474-4422(13)70293-xCitation Count: 646
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OPENTitle: Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3Journal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 111Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1312701111Best OA location URL: https://www.pnas.org/content/pnas/111/1/E34.full.pdfCitation Count: 114
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OPENTitle: Parkinson‘s Disease: What Role Do Pedunculopontine Cholinergic Neurons Play?Journal Name: Future NeurologyPublisher: Informa UK LimitedVol: 9Issue #: 1Start Page: 5End Page: 8Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.2217/fnl.13.61Best OA location URL: https://europepmc.org/articles/pmc5568855?pdf=renderCitation Count: 6
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OPENTitle: Neuropathologic Heterogeneity Does Not Impair Florbetapir-Positron Emission Tomography Postmortem CorrelatesJournal Name: Journal of Neuropathology & Experimental NeurologyPublisher: Oxford University Press (OUP)Vol: 73Issue #: 1Start Page: 72End Page: 80Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/nen.0000000000000028Best OA location URL: https://academic.oup.com/jnen/article-pdf/73/1/72/9563424/73-1-72.pdfCitation Count: 41
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OPENTitle: Atypical presentation of late‐onset Tay‐sachs diseaseJournal Name: Muscle & NervePublisher: WileyVol: 49Issue #: 5Start Page: 768End Page: 771Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mus.24146Best OA location URL: https://europepmc.org/articles/pmc4346308?pdf=renderCitation Count: 37
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OPENTitle: Pure hereditary spastic paraplegia due to a de novo mutation in the NIPA1 geneJournal Name: European Journal of NeurologyPublisher: WileyVol: 21Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/ene.12284Best OA location URL: https://europepmc.org/articles/pmc4138605?pdf=renderCitation Count: 8
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OPENTitle: Parkinson's Disease Biomarkers: Resources for Discovery and ValidationJournal Name: NeuropsychopharmacologyPublisher: Springer Science and Business Media LLCVol: 39Issue #: 1Start Page: 241End Page: 242Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/npp.2013.246Best OA location URL: https://www.nature.com/articles/npp2013246.pdfCitation Count: 6
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OPENTitle: Gait impairment precedes clinical symptoms in spinocerebellar ataxia type 6Journal Name: Movement DisordersPublisher: WileyVol: 29Issue #: 2Start Page: 252End Page: 255Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25706Best OA location URL: https://europepmc.org/articles/pmc6551218?pdf=renderCitation Count: 61
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RESTRICTEDTitle: The mitochondrial rhomboid protease: Its rise from obscurity to the pinnacle of disease-relevant genesJournal Name: Biochimica et Biophysica Acta (BBA) - BiomembranesPublisher: Elsevier BVVol: 1828Issue #: 12Start Page: 2916End Page: 2925Publication Date:Open Access(OA) Status: RESTRICTEDLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.bbamem.2013.05.012Best OA location URL: https://doi.org/10.1016/j.bbamem.2013.05.012Citation Count: 38
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OPENTitle: The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neuronsJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 127Issue #: 2Start Page: 283End Page: 295Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-013-1219-1Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-013-1219-1.pdfCitation Count: 32
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OPENTitle: Comparative study of the neurotrophic effects elicited by VEGF-B and GDNF in preclinical in vivo models of Parkinson’s diseaseJournal Name: NeurosciencePublisher: Elsevier BVVol: 258Issue #:Start Page: 385End Page: 400Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuroscience.2013.11.038Best OA location URL: https://europepmc.org/articles/pmc3923582?pdf=renderCitation Count: 51
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OPENTitle: Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamilyJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 23Issue #: 8Start Page: 2055End Page: 2077Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddt600Best OA location URL: https://academic.oup.com/hmg/article-pdf/23/8/2055/14143078/ddt600.pdfCitation Count: 124
- A comparative study of Parkinson's disease and leucine-rich repeat kinase 2 p.G2019S parkinsonism2013RESTRICTEDTitle: A comparative study of Parkinson's disease and leucine-rich repeat kinase 2 p.G2019S parkinsonismJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 35Issue #: 5Start Page: 1125End Page: 1131Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.11.015Citation Count: 83
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OPENTitle: Widespread sex differences in gene expression and splicing in the adult human brainJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/ncomms3771Best OA location URL: https://www.nature.com/articles/ncomms3771.pdfCitation Count: 294
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OPENTitle: Concordance and Discriminatory Power of Cough Measurement Devices for Individuals With Parkinson DiseaseJournal Name: ChestPublisher: Elsevier BVVol: 145Issue #: 5Start Page: 1089End Page: 1096Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1378/chest.13-0596Best OA location URL: https://europepmc.org/articles/pmc4011653?pdf=renderCitation Count: 24
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OPENTitle: A New Method for Quantitative Immunoblotting of Endogenous α-SynucleinJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 11Start Page: e81314End Page: e81314Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0081314Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0081314&type=printableCitation Count: 35
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OPENTitle: Rare variants in LRRK1 and Parkinson's diseaseJournal Name: neurogeneticsPublisher: Springer Science and Business Media LLCVol: 15Issue #: 1Start Page: 49End Page: 57Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s10048-013-0383-8Best OA location URL: https://link.springer.com/content/pdf/10.1007/s10048-013-0383-8.pdfCitation Count: 30
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RESTRICTEDTitle: Should impulse control disorders and dopamine dysregulation syndrome be indications for deep brain stimulation and intestinal levodopa?Journal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 14Start Page: 1915End Page: 1919Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.25735Best OA location URL: https://europepmc.org/articles/pmc3859686?pdf=renderCitation Count: 29
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OPENTitle: Loss of Leucine-Rich Repeat Kinase 2 (LRRK2) in Rats Leads to Progressive Abnormal Phenotypes in Peripheral OrgansJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 11Start Page: e80705End Page: e80705Publication Date:Open Access(OA) Status: OPENLicense: cc0DOI - Digital Object Identifier: 10.1371/journal.pone.0080705Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0080705&type=printableCitation Count: 178
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OPENTitle: Measurement of autophagy flux in the nervous system in vivoJournal Name: Cell Death & DiseasePublisher: Springer Science and Business Media LLCVol: 4Issue #: 11Start Page: e917End Page: e917Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/cddis.2013.421Best OA location URL: https://www.nature.com/articles/cddis2013421.pdfCitation Count: 111
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OPENTitle: DNAJC13 mutations in Parkinson diseaseJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol: 23Issue #: 7Start Page: 1794End Page: 1801Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/hmg/ddt570Best OA location URL: https://europepmc.org/articles/pmc3999380?pdf=renderCitation Count: 295
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OPENTitle: Dysregulation of glucose metabolism is an early event in sporadic Parkinson's diseaseJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 35Issue #: 5Start Page: 1111End Page: 1115Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.11.001Best OA location URL: https://doi.org/10.1016/j.neurobiolaging.2013.11.001Citation Count: 210
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RESTRICTEDTitle: Tissue transglutaminase in Alzheimer's disease – facts and fiction: a reply to “Tissue transglutaminase is a biochemical marker for Alzheimer's disease”Journal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 35Issue #: 4Start Page: e5End Page: e9Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2013.09.042Citation Count: 14
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OPENTitle: GTP binding controls complex formation by the human ROCO protein MASL1Journal Name: The FEBS JournalPublisher: WileyVol: 281Issue #: 1Start Page: 261End Page: 274Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1111/febs.12593Best OA location URL: https://europepmc.org/articles/pmc3995007?pdf=renderCitation Count: 13
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OPENTitle: Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvationJournal Name: Biochemical and Biophysical Research CommunicationsPublisher: Elsevier BVVol: 441Issue #: 4Start Page: 862End Page: 866Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.bbrc.2013.10.159Best OA location URL: https://doi.org/10.1016/j.bbrc.2013.10.159Citation Count: 82
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OPENTitle: Association of Parkinson Disease with Structural and Regulatory Variants in the HLA RegionJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 93Issue #: 5Start Page: 984End Page: 993Publication Date:Open Access(OA) Status: OPENLicense: elsevier-specific: oa user licenseDOI - Digital Object Identifier: 10.1016/j.ajhg.2013.10.009Best OA location URL: http://www.cell.com/article/S0002929713004667/pdfCitation Count: 167
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OPENTitle: SMG1 Identified as a Regulator of Parkinson’s Disease-Associated alpha-Synuclein through siRNA ScreeningJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 10Start Page: e77711End Page: e77711Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0077711Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0077711&type=printableCitation Count: 17
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OPENTitle: Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-onesJournal Name: European Journal of Medicinal ChemistryPublisher: Elsevier BVVol: 70Issue #:Start Page: 758End Page: 767Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.ejmech.2013.10.052Best OA location URL: https://doi.org/10.1016/j.ejmech.2013.10.052Citation Count: 46
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OPENTitle: Integrative Pathway-Based Approach for Genome-Wide Association Studies: Identification of New Pathways for Rheumatoid Arthritis and Type 1 DiabetesJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 10Start Page: e78577End Page: e78577Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0078577Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0078577&type=printableCitation Count: 10
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OPENTitle: Over‐expression of an inactive mutant cathepsin D increases endogenous alpha‐synuclein and cathepsin B activity in SH‐SY5Y cellsJournal Name: Journal of NeurochemistryPublisher: WileyVol: 128Issue #: 6Start Page: 950End Page: 961Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jnc.12497Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12497Citation Count: 38
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OPENTitle: Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesiaJournal Name: Neuroscience ResearchPublisher: Elsevier BVVol: 77Issue #: 4Start Page: 242End Page: 246Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.neures.2013.10.002Citation Count: 46
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OPENTitle: Parkinson disease phenotype in Ashkenazi jews with and without LRRK2 G2019S mutationsJournal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 14Start Page: 1966End Page: 1971Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.25647Best OA location URL: https://europepmc.org/articles/pmc3859844?pdf=renderCitation Count: 135
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OPENTitle: The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantationJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 62Issue #:Start Page: 233End Page: 240Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2013.09.021Best OA location URL: https://lup.lub.lu.se/search/files/1604585/4934203.pdfCitation Count: 19
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OPENTitle: Phosphoproteomic evaluation of pharmacological inhibition of leucine‐rich repeat kinase 2 reveals significant off‐target effects of LRRK‐2‐IN‐1Journal Name: Journal of NeurochemistryPublisher: WileyVol: 128Issue #: 4Start Page: 561End Page: 576Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1111/jnc.12483Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.12483Citation Count: 63
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OPENTitle: Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degenerationJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 127Issue #: 2Start Page: 271End Page: 282Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s00401-013-1193-7Best OA location URL: https://europepmc.org/articles/pmc3943649?pdf=renderCitation Count: 77
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OPENTitle: Herp depletion protects from protein aggregation by up-regulating autophagyJournal Name: Biochimica et Biophysica Acta (BBA) - Molecular Cell ResearchPublisher: Elsevier BVVol: 1833Issue #: 12Start Page: 3295End Page: 3305Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.bbamcr.2013.09.006Best OA location URL: https://doi.org/10.1016/j.bbamcr.2013.09.006Citation Count: 37
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OPENTitle: Tardive Dyskinesia: Therapeutic Options for an Increasingly Common DisorderJournal Name: NeurotherapeuticsPublisher: Elsevier BVVol: 11Issue #: 1Start Page: 166End Page: 176Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s13311-013-0222-5Best OA location URL: https://europepmc.org/articles/pmc3899488?pdf=renderCitation Count: 103
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RESTRICTEDTitle: Dopamine overdose hypothesis: Evidence and clinical implicationsJournal Name: Movement DisordersPublisher: WileyVol: 28Issue #: 14Start Page: 1920End Page: 1929Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.25687Best OA location URL: https://europepmc.org/articles/pmc3859825?pdf=renderCitation Count: 135
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RESTRICTEDTitle: The regulation and deregulation of Wnt signaling by PARK genes in health and diseaseJournal Name: Journal of Molecular Cell BiologyPublisher: Oxford University Press (OUP)Vol: 6Issue #: 1Start Page: 3End Page: 12Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1093/jmcb/mjt037Best OA location URL: https://academic.oup.com/jmcb/article-pdf/6/1/3/2590207/mjt037.pdfCitation Count: 63
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OPENTitle: Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrinJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 62Issue #:Start Page: 172End Page: 178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2013.09.019Best OA location URL: https://europepmc.org/articles/pmc3968945?pdf=renderCitation Count: 78
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RESTRICTEDTitle: Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkersJournal Name: Brain Imaging and BehaviorPublisher: Springer Science and Business Media LLCVol: 8Issue #: 2Start Page: 183End Page: 207Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.1007/s11682-013-9262-zBest OA location URL: https://link.springer.com/content/pdf/10.1007/s11682-013-9262-z.pdfCitation Count: 148
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OPENTitle: Coordinate Regulation of Mature Dopaminergic Axon Morphology by Macroautophagy and the PTEN Signaling PathwayJournal Name: PLoS GeneticsPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 10Start Page: e1003845End Page: e1003845Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pgen.1003845Best OA location URL: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1003845&type=printableCitation Count: 19