MJFF Publications

Association of Misfolded α-Synuclein Derived from Neuronal Exosomes in Blood with Parkinson’s Disease Diagnosis and Duration

2024

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Title: Association of Misfolded α-Synuclein Derived from Neuronal Exosomes in Blood with Parkinson’s Disease Diagnosis and Duration

Author(s): Eva Schaeffer, Annika Kluge, Claudia Schulte, Christian Deuschle, Josina Bunk, Julius Welzel, Walter Maetzler, Daniela Berg

Journal Name: Journal of Parkinson's Disease

Publisher: IOS Press

Vol: 14

Issue #: 4

Start Page: 1

End Page: 13

Publication Date: 2024-04-24

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-230390

Best OA location URL: https://content.iospress.com:443/download/journal-of-parkinsons-disease/jpd230390?id=journal-of-parkinsons-disease%2Fjpd230390

Citation Count: 4

Changes in Oxidised Phospholipids in Response to Oxidative Stress in Microtubule-Associated Protein Tau (MAPT) Mutant Dopamine Neurons

2024

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Title: Changes in Oxidised Phospholipids in Response to Oxidative Stress in Microtubule-Associated Protein Tau (MAPT) Mutant Dopamine Neurons

Author(s): Xanthe Bradford, Hugo J. R. Fernandes, Stuart G. Snowden

Journal Name: Antioxidants

Publisher: MDPI AG

Vol: 13

Issue #: 5

Start Page: 508

End Page: 508

Publication Date: 2024-04-24

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3390/antiox13050508

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Citation Count: 0

Perspectives of People At-Risk on Parkinson’s Prevention Research

2024

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Title: Perspectives of People At-Risk on Parkinson’s Prevention Research

Author(s): Jessi L. Keavney, Soania Mathur, Karlin Schroeder, Ray Merrell, Sergio A. Castillo‐Torres, Virginia Gao, Grace F. Crotty, Michael A. Schwarzschild, John M. Poma

Journal Name: Journal of Parkinson's Disease

Publisher: IOS Press

Vol: 14

Issue #: 3

Start Page: 399

End Page: 414

Publication Date: 2024-04-23

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-230436

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Citation Count: 2

Prospective Role of PAK6 and 14-3-3γ as Biomarkers for Parkinson’s Disease

2024

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Title: Prospective Role of PAK6 and 14-3-3γ as Biomarkers for Parkinson’s Disease

Author(s): Elena Giusto, Lorenza Maistrello, Lucia Iannotta, Veronica Giusti, Ludovica Iovino, Rina Bandopadhyay, Angelo Antonini, Luigi Bubacco, R. Barresi, Nicoletta Plotegher, Elisa Greggio, Laura Civiero

Journal Name: Journal of Parkinson's Disease

Publisher: IOS Press

Vol: 14

Issue #: 3

Start Page: 495

End Page: 506

Publication Date: 2024-04-23

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.3233/jpd-230402

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Citation Count: 0

Development and Implementation of an Innovative Framework for Automated Radiomics Analysis in Neuroimaging

2024

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Title: Development and Implementation of an Innovative Framework for Automated Radiomics Analysis in Neuroimaging

Author(s): C. Camastra, Giovanni Pasini, Alessandro Stefano, G. Russo, Basilio Vescio, Fabiano Bini, Franco Marinozzi, Antonio Augimeri

Journal Name: Journal of Imaging

Publisher: MDPI AG

Vol: 10

Issue #: 4

Start Page: 96

End Page: 96

Publication Date: 2024-04-22

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3390/jimaging10040096

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Citation Count: 0

Longitudinal cognitive decline characterizes the profile of non-PD-manifest GBA1 mutation carriers

2024

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Title: Longitudinal cognitive decline characterizes the profile of non-PD-manifest GBA1 mutation carriers

Author(s): Benjamin Röeben, Inga Liepelt‐Scarfone, Stefanie Lerche, Milan Zimmermann, Isabel Wurster, Ulrike Suenkel, Claudia Schulte, Christian Deuschle, Thomas Leyhe, Walter Maetzler, Thomas Gasser, Daniela Berg, Kathrin Brockmann

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-22

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00706-1

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Citation Count: 1

Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons

2024

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Title: Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons

Author(s): Nisha Mohd Rafiq, Kenshiro Fujise, Martin T. W. Rosenfeld, Peng Xu, Pietro De Camilli

Journal Name: Proceedings of the National Academy of Sciences

Publisher: Proceedings of the National Academy of Sciences

Vol: 121

Issue #: 17

Start Page:

End Page:

Publication Date: 2024-04-18

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1073/pnas.2318943121

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Citation Count: 3

Predicting the occurrence of mild cognitive impairment in Parkinson’s disease using structural MRI data

2024

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Title: Predicting the occurrence of mild cognitive impairment in Parkinson’s disease using structural MRI data

Author(s): Iman Beheshti, Ji Hyun Ko

Journal Name: Frontiers in Neuroscience

Publisher: Frontiers Media SA

Vol: 18

Issue #:

Start Page:

End Page:

Publication Date: 2024-04-18

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3389/fnins.2024.1375395

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Citation Count: 0

Resequencing the complete SNCA locus in Indian patients with Parkinson’s disease

2024

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Title: Resequencing the complete SNCA locus in Indian patients with Parkinson’s disease

Author(s): Asha Kishore, Marc Sturm, Kanchana Soman Pillai, Christopher Hakkaart, Divya Kalikavil Puthanveedu, Madhusoodanan Urulangodi, Syam Krishnan, Ashwin Ashok Kumar Sreelatha, Roopa Rajan, Pramod Kumar Pal, Ravi Yadav, Gangadhara Sarma, Nicolas Casadei, Thomas Gasser, Peter Bauer, Olaf Riess, Manu Sharma

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-15

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00676-4

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Citation Count: 0

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

2024

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Title: Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

Author(s): Quyen Do, Humaira Noor, Ricardo Márquez-Gómez, Kaitlyn M. L. Cramb, Bryan Ng, Ajantha Abey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa‐Vergniory, Richard Wade‐Martins

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-12

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00694-2

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Citation Count: 2

Self-supervised learning for human activity recognition using 700,000 person-days of wearable data

2024

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Title: Self-supervised learning for human activity recognition using 700,000 person-days of wearable data

Author(s): Hang Yuan, Shing Chan, Andrew P. Creagh, Catherine Tong, Aidan Acquah, David A. Clifton, Aiden Doherty

Journal Name: npj Digital Medicine

Publisher: Springer Science and Business Media LLC

Vol: 7

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-12

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41746-024-01062-3

Best OA location URL: https://www.nature.com/articles/s41746-024-01062-3.pdf

Citation Count: 5

Predictors of stress resilience in Parkinson’s disease and associations with symptom progression

2024

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Title: Predictors of stress resilience in Parkinson’s disease and associations with symptom progression

Author(s): Anouk van der Heide, Lisanne J. Dommershuijsen, Lara Puhlmann, Raffaël Kalisch, Bastiaan R. Bloem, Anne Speckens, Rick C. Helmich

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-11

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00692-4

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Citation Count: 8

Mitochondrial import stress and PINK1-mediated mitophagy: the role of the PINK1-TOMM-TIMM23 supercomplex

2024

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Title: Mitochondrial import stress and PINK1-mediated mitophagy: the role of the PINK1-TOMM-TIMM23 supercomplex

Author(s): Mohamed A. Eldeeb, Armaan Fallahi, Andrea Soumbasis, Andrew N. Bayne, Jean‐François Trempe, Edward A. Fon

Journal Name: Autophagy

Publisher: Informa UK Limited

Vol: 20

Issue #: 8

Start Page: 1903

End Page: 1905

Publication Date: 2024-04-10

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1080/15548627.2024.2340399

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Citation Count: 0

Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in aDrosophilaknock-in tauopathy model

2024

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Title: Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in aDrosophilaknock-in tauopathy model

Author(s): Hassan Bukhari, Vanitha Nithianadam, Rachel A. Battaglia, Anthony Cicalo, Souvarish Sarkar, Aram Comjean, Yanhui Hu, Matthew Leventhal, Xianjun Dong, Mel Β. Feany

Journal Name: Genome Research

Publisher: Cold Spring Harbor Laboratory

Vol:

Issue #:

Start Page: gr.278576.123

End Page: gr.278576.123

Publication Date: 2024-04-10

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1101/gr.278576.123

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Citation Count: 0

Visualizing chaperone-mediated multistep assembly of the human 20S proteasome

2024

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Title: Visualizing chaperone-mediated multistep assembly of the human 20S proteasome

Author(s): Frank Adolf, Jiale Du, Ellen A. Goodall, Richard M. Walsh, Shaun Rawson, Susanne von Gronau, J. Wade Harper, John Hanna, Brenda A. Schulman

Journal Name: Nature Structural & Molecular Biology

Publisher: Springer Science and Business Media LLC

Vol: 31

Issue #: 8

Start Page:

End Page:

Publication Date: 2024-04-10

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41594-024-01268-9

Best OA location URL: https://www.nature.com/articles/s41594-024-01268-9.pdf

Citation Count: 2

Biological Staging of the Parkinson’s Progression Markers Initiative (PPMI) Cohort Using the Research Neuronal α-synuclein Disease Integrated Staging System (NSD-ISS) (P11-3.009)

2024

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Title: Biological Staging of the Parkinson’s Progression Markers Initiative (PPMI) Cohort Using the Research Neuronal α-synuclein Disease Integrated Staging System (NSD-ISS) (P11-3.009)

Author(s): Caroline M. Tanner, Tanya Simuni, Lana M. Chahine, Kathleen L. Poston, Michael C. Brumm, Sohini Chowdry, Jean‐Christophe Corvol, Luis Concha‐Marambio, Tien Dam, Peter DiBiaso, Tatiana Foroud, Mark Frasier, Caroline Gochanour, Danna Jennings, Karl Kieburtz, Catherine Kopil, Kalpana Merchant, Brit Mollenhauer, Thomas J. Montine, Kelly Nudelman, Gennaro Pagano, John Seibyl, Todd Sherer, Andrew Singleton, Diane Stephenson, Matthew Stern, Claudio Soto, Eduardo Tolosa, Daniel Weintraub, Yuge Xiao, Andrew Siderowf, Werner Poewe, Kenneth Marek

Journal Name: Neurology

Publisher: Ovid Technologies (Wolters Kluwer Health)

Vol: 102

Issue #: 17_supplement_1

Start Page:

End Page:

Publication Date: 2024-04-09

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1212/wnl.0000000000204771

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Citation Count: 0

RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds

2024

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Title: RASP: Optimal Single Puncta Detection in Complex Cellular Backgrounds

Author(s): Bin Fu, Emma E. Brock, Rebecca Andrews, Jonathan C. Breiter, Ru Tian, Christina E. Toomey, Joanne Lachica, Tammaryn Lashley, Mina Ryten, Nicholas Wood, Michele Vendruscolo, Sonia Gandhi, Lucien E. Weiss, Joseph S. Beckwith, Steven F. Lee

Journal Name: The Journal of Physical Chemistry B

Publisher: American Chemical Society (ACS)

Vol: 128

Issue #: 15

Start Page: 3585

End Page: 3597

Publication Date: 2024-04-09

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1021/acs.jpcb.4c00174

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Citation Count: 0

Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders

2024

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Title: Rational design of structure‐based vaccines targeting misfolded alpha‐synuclein conformers of Parkinson's disease and related disorders

Author(s): José Miguel Flores-Fernández, Verena Pesch, Aishwarya Sriraman, Enrique Chimal-Juárez, Sara Amidian, Xiongyao Wang, Caleb Duckering, Andrew Fang, Sara Reithofer, Liang Ma, Leonardo M. Cortez, Valerie L. Sim, Gültekin Tamgüney, Holger Wille

Journal Name: Bioengineering & Translational Medicine

Publisher: Wiley

Vol: 9

Issue #: 4

Start Page:

End Page:

Publication Date: 2024-04-09

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1002/btm2.10665

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Citation Count: 0

[125I]IPC-Lecanemab: Synthesis and Evaluation of Aβ-Plaque-Binding Antibody and Comparison with Small-Molecule [18F]Flotaza and [125I]IBETA in Postmortem Human Alzheimer’s Disease

2024

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Title: [125I]IPC-Lecanemab: Synthesis and Evaluation of Aβ-Plaque-Binding Antibody and Comparison with Small-Molecule [18F]Flotaza and [125I]IBETA in Postmortem Human Alzheimer’s Disease

Author(s): Christopher Liang, Cayz G. Paclibar, Noresa L. Gonzaga, Stephanie A. Sison, Harman S. Bath, Agnes P. Biju, Jogeshwar Mukherjee

Journal Name: Neurology International

Publisher: MDPI AG

Vol: 16

Issue #: 2

Start Page: 419

End Page: 431

Publication Date: 2024-04-08

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3390/neurolint16020031

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Citation Count: 3

Factors Influencing Patient Disclosure of Parkinson's Disease Genetic Testing Results to Relatives

2024

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Title: Factors Influencing Patient Disclosure of Parkinson's Disease Genetic Testing Results to Relatives

Author(s): Jeanine Schulze, Jasmine Kaur Dhaliwal, Mandy Miller, Emily A. Quinn, Leah Wetherill, Lola Cook

Journal Name: Movement Disorders Clinical Practice

Publisher: Wiley

Vol: 11

Issue #: 7

Start Page: 786

End Page: 794

Publication Date: 2024-04-08

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.1002/mdc3.14043

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Citation Count: 0

A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy

2024

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Title: A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy

Author(s): Dan Tudorica, Bishal Basak, Alexia S. Puerta Cordova, Grace Khuu, Kevin Rose, Michael Lazarou, Erika L.F. Holzbaur, James H. Hurley

Journal Name: Journal of Cell Biology

Publisher: Rockefeller University Press

Vol: 223

Issue #: 7

Start Page:

End Page:

Publication Date: 2024-04-06

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1083/jcb.202309015

Best OA location URL: https://rupress.org/jcb/article-pdf/223/7/e202309015/1928200/jcb_202309015.pdf

Citation Count: 4

An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

2024

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Title: An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

Author(s): Marie‐France Dorion, Diana Casas, Irina Shlaifer, Moein Yaqubi, Peter Fleming, Nathan Karpilovsky, Carol X.‐Q. Chen, Michaël Nicouleau, Valerio E. C. Piscopo, Emma J. MacDougall, Aeshah Alluli, Taylor Goldsmith, Alexandria Schneider, Sonia Dorion, Nathalia Aprahamian, Adam MacDonald, Rhalena A. Thomas, Roy Dudley, Jeffrey A. Hall, Edward A. Fon, Jack P. Antel, Jo Anne Stratton, Thomas M. Durcan, Roberta La Piana, Luke M. Healy

Journal Name: Molecular Neurodegeneration

Publisher: Springer Science and Business Media LLC

Vol: 19

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-05

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1186/s13024-024-00723-x

Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-024-00723-x

Citation Count: 0

Fusion of biomedical imaging studies for increased sample size and diversity: a case study of brain MRI

2024

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Title: Fusion of biomedical imaging studies for increased sample size and diversity: a case study of brain MRI

Author(s): Matias Aiskovich, Eduardo Castro, Jenna Reinen, Shreyas Fadnavis, Anushree Mehta, Hongyang Li, Amit Dhurandhar, Guillermo Cecchi, Pablo Polosecki

Journal Name: Frontiers in Radiology

Publisher: Frontiers Media SA

Vol: 4

Issue #:

Start Page:

End Page:

Publication Date: 2024-04-05

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.3389/fradi.2024.1283392

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Citation Count: 0

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

2024

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Title: Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Author(s): Jean-Louis Parmasad, Konrad M. Ricke, Benjamin Nguyen, Morgan G. Stykel, Brodie Buchner-Duby, Amanda S. Bruce, Haley Geertsma, Eric Lian, Nathalie A. Lengacher, Steve Callaghan, Alvin Joselin, Julianna J. Tomlinson, Michael G. Schlossmacher, William L. Stanford, Jiyan Ma, Patrik Brundin, Scott D. Ryan, Maxime W.C. Rousseaux

Journal Name: Cell Death & Disease

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 4

Start Page:

End Page:

Publication Date: 2024-04-04

Open Access(OA) Status: RESTRICTED

License: cc-by, cc-by

DOI - Digital Object Identifier: 10.1038/s41419-024-06534-8

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Citation Count: 1

Orthogonal analysis of mitochondrial function in Parkinson’s disease patients

2024

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Title: Orthogonal analysis of mitochondrial function in Parkinson’s disease patients

Author(s): Sander Barnhoorn, Chiara Milanese, Tracy Li, Lone Dons, Mehrnaz Ghazvini, M. Sette, Stefania Farina, Daisy Sproviero, César Payán‐Gómez, Pier G. Mastroberardino

Journal Name: Cell Death & Disease

Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 4

Start Page:

End Page:

Publication Date: 2024-04-03

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41419-024-06617-6

Best OA location URL: https://www.nature.com/articles/s41419-024-06617-6.pdf

Citation Count: 0

RedOx regulation of LRRK2 kinase activity by active site cysteines

2024

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Title: RedOx regulation of LRRK2 kinase activity by active site cysteines

Author(s): Chiara R. Trilling, Jui-Hung Weng, Pallavi Kaila Sharma, Viktoria Nolte, Jian Wu, Wen Ma, Daniela Boassa, Susan S. Taylor, Friedrich W. Herberg

Journal Name: npj Parkinson's Disease

Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-03

Open Access(OA) Status: RESTRICTED

License: cc-by

DOI - Digital Object Identifier: 10.1038/s41531-024-00683-5

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Citation Count: 2

Alterations in Blood Methylome as Potential Epigenetic Biomarker in Sporadic Parkinson's Disease

2024

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Title: Alterations in Blood Methylome as Potential Epigenetic Biomarker in Sporadic Parkinson's Disease

Author(s): Paulina González-Latapí, Bernabé I. Bustos, Siyuan Dong, Steven Lubbe, Tanya Simuni, Dimitri Krainc

Journal Name: Annals of Neurology

Publisher: Wiley

Vol: 95

Issue #: 6

Start Page: 1162

End Page: 1172

Publication Date: 2024-04-02

Open Access(OA) Status: RESTRICTED

License: cc-by-nc-nd

DOI - Digital Object Identifier: 10.1002/ana.26923

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Citation Count: 1

An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer’s Disease

2024

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Title: An X Chromosome Transcriptome Wide Association Study Implicates ARMCX6 in Alzheimer’s Disease

Author(s): Xueyi Zhang, Lissette Gomez, Jennifer E. Below, Adam C. Naj, Eden R. Martin, Brian W. Kunkle, William S. Bush

Journal Name: Journal of Alzheimer's Disease

Publisher: IOS Press

Vol: 98

Issue #: 3

Start Page: 1053

End Page: 1067

Publication Date: 2024-04-02

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.3233/jad-231075

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Citation Count: 2

DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson’s disease

2024

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Title: DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson’s disease

Author(s): Seong‐Jin Yu, Yun Wang, Hui Shen, Eun-Kyung Bae, Yazhou Li, Kumar Sambamurti, Michael A. Tones, Margaret M. Zaleska, Barry J. Hoffer, Nigel H. Greig

Journal Name: GeroScience

Publisher: Springer Science and Business Media LLC

Vol: 46

Issue #: 5

Start Page:

End Page:

Publication Date: 2024-04-02

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1007/s11357-024-01116-0

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Citation Count: 1

Identification and structural characterization of small molecule inhibitors of PINK1

2024

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Title: Identification and structural characterization of small molecule inhibitors of PINK1

Author(s): Shafqat Rasool, Tara Shomali, Luc Truong, Nathalie Croteau, Simon Veyron, Bernardo A. Bustillos, Wolfdieter Springer, Fabienne C. Fiesel, Jean‐François Trempe

Journal Name: Scientific Reports

Publisher: Springer Science and Business Media LLC

Vol: 14

Issue #: 1

Start Page:

End Page:

Publication Date: 2024-04-02

Open Access(OA) Status: RESTRICTED

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DOI - Digital Object Identifier: 10.1038/s41598-024-58285-3

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Citation Count: 0

Real-World Experiences of Parkinson's Disease OFF Time and Role of Demographics

2024

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Title: Real-World Experiences of Parkinson's Disease OFF Time and Role of Demographics

Author(s): Radhika Devraj, Ahmad El Kouzi, Marlon R. Tracey

Journal Name: Journal of Patient-Centered Research and Reviews

Publisher: Aurora Health Care, Inc.

Vol: 11

Issue #: 1

Start Page: 8

End Page: 17

Publication Date: 2024-04-02

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DOI - Digital Object Identifier: 10.17294/2330-0698.2057

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Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology

2024

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Title: Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology

Author(s): Lara Blömeke, Fabian Rehn, Victoria Kraemer‐Schulien, Janine Kutzsche, Marlene Pils, Tuyen Bujnicki, Piotr Lewczuk, Johannes Kornhuber, Silka Dawn Freiesleben, Luisa‐Sophie Schneider, Lukas Preis, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Andrea Lohse, Anja Schneider, Klaus Fließbach, Jens Wiltfang, Niels Hansen, Ayda Rostamzadeh, Emrah Düzel, Wenzel Glanz, Enise I. Incesoy, Michaela Butryn, Katharina Büerger, Daniel Janowitz, Michael Ewers, Robert Perneczky, Boris‐Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Göerß, Christoph Laske, Matthias H. Munk, Carolin Sanzenbacher, Annika Spottke, Nina Roy‐Kluth, Michael T. Heneka, Frederic Brosseron, Michael Wagner, Steffen Wolfsgruber, Luca Kleineidam, Melina Stark, Matthias Schmid, Frank Jessen, Oliver Bannach, Dieter Willbold, Oliver Peters

Journal Name: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring

Publisher: Wiley

Vol: 16

Issue #: 2

Start Page:

End Page:

Publication Date: 2024-04-01

Open Access(OA) Status: RESTRICTED

License: cc-by-nc

DOI - Digital Object Identifier: 10.1002/dad2.12589

Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/dad2.12589

Citation Count: 0

Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease

2024

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Title: Experimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease

Author(s): Martin Hart, Fabian Kern, Claudia Fecher‐Trost, Lena Krammes, Ernesto Aparicio‐Puerta, Annika Engel, Pascal Hirsch, Viktoria Wagner, Verena Keller, Georges Pierre Schmartz, Stefanie Rheinheimer, Caroline Diener, Ulrike Fischer, Jens Mayer, Markus R. Meyer, Veit Flockerzi, Andreas Keller, Eckart Meese

Journal Name: Experimental & Molecular Medicine

Publisher: Springer Science and Business Media LLC

Vol: 56

Issue #: 4

Start Page: 935

End Page: 945

Publication Date: 2024-04-01

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DOI - Digital Object Identifier: 10.1038/s12276-024-01202-5

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Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains

2024

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Title: Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains

Author(s): Gregory A. Cary, Jesse C. Wiley, Jake Gockley, S. Keegan, Sai Sruthi Amirtha Ganesh, Laura Heath, Robert R. Butler, Lara M. Mangravite, Benjamin A. Logsdon, Frank M. Longo, Allan I. Levey, Anna K Greenwood, Gregory W. Carter

Journal Name: Alzheimer's & Dementia: Translational Research & Clinical Interventions

Publisher: Wiley

Vol: 10

Issue #: 2

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Publication Date: 2024-04-01

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DOI - Digital Object Identifier: 10.1002/trc2.12461

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Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease

2024

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Title: Prasinezumab slows motor progression in rapidly progressing early-stage Parkinson’s disease

Author(s): Gennaro Pagano, Kirsten I. Taylor, Judith Cabrera, Tanya Simuni, Kenneth Marek, Ronald B. Postuma, Nicola Pavese, Fabrizio Stocchi, Kathrin Brockmann, Hanno Svoboda, Dylan Trundell, Annabelle Monnet, Rachelle S. Doody, Paulo Fontoura, Geoffrey A. Kerchner, Patrik Brundin, Tania Nikolcheva, Azad Bonni

Journal Name: Nature Medicine

Publisher: Springer Science and Business Media LLC

Vol: 30

Issue #: 4

Start Page: 1096

End Page: 1103

Publication Date: 2024-04-01

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DOI - Digital Object Identifier: 10.1038/s41591-024-02886-y

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RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction

2024

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Title: RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction

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Journal Name: Neurobiology of Disease

Publisher: Elsevier BV

Vol: 196

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Start Page: 106514

End Page: 106514

Publication Date: 2024-04-01

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DOI - Digital Object Identifier: 10.1016/j.nbd.2024.106514

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The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia

2024

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Title: The integrated stress response pathway and neuromodulator signaling in the brain: lessons learned from dystonia

Author(s): Nicole Calakos, Zachary F. Caffall

Journal Name: Journal of Clinical Investigation

Publisher: American Society for Clinical Investigation

Vol: 134

Issue #: 7

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Publication Date: 2024-04-01

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DOI - Digital Object Identifier: 10.1172/jci177833

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Investigating the aspect of asymmetry in brain-first versus body-first Parkinson’s disease

2024

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Title: Investigating the aspect of asymmetry in brain-first versus body-first Parkinson’s disease

Author(s): Sofie Lövdal, Giulia Carli, Beatrice Orso, Michael Biehl, Dario Arnaldi, Pietro Mattioli, Annette Janzen, Elisabeth Sittig, Silvia Morbelli, Jan Booij, Wolfgang H. Oertel, Klaus L. Leenders, Sanne K. Meles

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Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

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Publication Date: 2024-03-30

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DOI - Digital Object Identifier: 10.1038/s41531-024-00685-3

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Genotype–phenotype correlation in PRKN-associated Parkinson’s disease

2024

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Title: Genotype–phenotype correlation in PRKN-associated Parkinson’s disease

Author(s): Poornima Jayadev Menon, Louise‐Laure Mariani, Baptiste Criniere-Boizet, Thomas Courtin, Christelle Tesson, Fanny Casse, Melanie Ferrien, Louise‐Laure Mariani, Stéphanie Carvalho, François‐Xavier Lejeune, Sana Rebbah, Gaspard Martet, Marion Houot, Aymeric Lanore, Graziella Mangone, Emmanuel Roze, Marie Vidailhet, Jan Aasly, Ziv Gan‐Or, Eric Yu, Yves Dauvilliers, Alexander Zimprich, Volker Tomantschger, Walter Pirker, Ignacio Álvarez, Pau Pástor, Alessio Di Fonzo, Kailash P. Bhatia, Francesca Magrinelli, Henry Houlden, Raquel Real, Andrea Quattrone, Patricia Limousin, Prasad Korlipara, Thomas Foltynie, Donald G. Grosset, Nigel Williams, Derek P. Narendra, Hsin-Pin Lin, Čarna Jovanović, Marina Svetel, Timothy Lynch, Amy Gallagher, Wim Vandenberghe, Thomas Gasser, Kathrin Brockmann, Huw R. Morris, Max Borsche, Christine Klein, Olga Corti, Alexis Brice, Suzanne Lesage, Jean‐Christophe Corvol

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Publisher: Springer Science and Business Media LLC

Vol: 10

Issue #: 1

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Publication Date: 2024-03-29

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DOI - Digital Object Identifier: 10.1038/s41531-024-00677-3

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Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

2024

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Title: Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue

Author(s): Dhruva Dhavale, Alexander M. Barclay, Collin G. Borcik, Katherine Basore, Dominik Berthold, Isabelle R. Gordon, Jialu Liu, Moses H. Milchberg, Jennifer Yu, Michaël Rau, Zachary Smith, Soumyo Sen, Brock Summers, John W. Smith, Owen A. Warmuth, Richard J. Perrin, Joel S. Perlmutter, Qian Chen, James A. J. Fitzpatrick, Charles D. Schwieters, Emad Tajkhorshid, Chad M. Rienstra, Paul T. Kotzbauer

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Publisher: Springer Science and Business Media LLC

Vol: 15

Issue #: 1

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Publication Date: 2024-03-29

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DOI - Digital Object Identifier: 10.1038/s41467-024-46832-5

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Development and characterization of a non-human primate model of disseminated synucleinopathy

2024

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Title: Development and characterization of a non-human primate model of disseminated synucleinopathy

Author(s): Alberto J. Rico, Almudena Corcho, Julia Chocarro, Goiaz Ariznabarreta, Elvira Roda, Adriana Honrubia, Patricia Arnáiz Castro, José L. Lanciego

Journal Name: Frontiers in Neuroanatomy

Publisher: Frontiers Media SA

Vol: 18

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Publication Date: 2024-03-27

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DOI - Digital Object Identifier: 10.3389/fnana.2024.1355940

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Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease

2024

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Title: Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease

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Publisher: Cold Spring Harbor Laboratory

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DOI - Digital Object Identifier: 10.1101/2024.03.22.586364

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Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2

2024

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Title: Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2

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Publisher: Cold Spring Harbor Laboratory

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DOI - Digital Object Identifier: 10.1101/2024.03.26.586828

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Single-cell multiplex chromatin and RNA interactions in ageing human brain

2024

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Title: Single-cell multiplex chromatin and RNA interactions in ageing human brain

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Journal Name: Nature

Publisher: Springer Science and Business Media LLC

Vol: 628

Issue #: 8008

Start Page: 648

End Page: 656

Publication Date: 2024-03-27

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DOI - Digital Object Identifier: 10.1038/s41586-024-07239-w

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Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

2024

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Title: Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

Author(s): Yazhou Li, Kelli L. Vaughan, Yun Wang, Seong‐Jin Yu, Eun-Kyung Bae, Ian A. Tamargo, Katherine O. Kopp, David Tweedie, Cheng‐Chuan Chiang, Keith T. Schmidt, Debomoy K. Lahiri, Michael A. Tones, Margaret M. Zaleska, Barry J. Hoffer, Julie A. Mattison, Nigel H. Greig

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Vol: 46

Issue #: 5

Start Page: 4397

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Publication Date: 2024-03-27

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DOI - Digital Object Identifier: 10.1007/s11357-024-01120-4

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TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

2024

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Title: TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

Author(s): Edward N. Wilson, Edward N. Wilson, Michelle S. Swarovski, Kristy A. Zera, Hannah E. Ennerfelt, Qian Wang, Aisling M. Chaney, Esha Gauba, Javier A. Ramos Benitez, Yann Le Guen, Paras S. Minhas, Maharshi Panchal, Yuting Tan, Eran Blacher, Chinyere Agbaegbu Iweka, Haley C. Cropper, Poorva Jain, Qingkun Liu, Swapnil Mehta, Abigail J. Zuckerman, Matthew Xin, Jacob Umans, Jolie Huang, Aarooran S. Durairaj, Geidy E. Serrano, Thomas G. Beach, Michael D. Greicius, Michelle L. James, Marion S. Buckwalter, Melanie R. McReynolds, Joshua D. Rabinowitz, Katrin I. Andreasson

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Publisher: Springer Science and Business Media LLC

Vol: 27

Issue #: 5

Start Page: 873

End Page: 885

Publication Date: 2024-03-27

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DOI - Digital Object Identifier: 10.1038/s41593-024-01610-w

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Parkinson’s Disease is Predominantly a Genetic Disease

2024

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Title: Parkinson’s Disease is Predominantly a Genetic Disease

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Journal Name: Journal of Parkinson's Disease

Publisher: IOS Press

Vol: 14

Issue #: 3

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End Page: 482

Publication Date: 2024-03-26

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DOI - Digital Object Identifier: 10.3233/jpd-230376

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Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology

2024

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Title: Spatial transcriptomics reveals molecular dysfunction associated with cortical Lewy pathology

Author(s): Thomas J. Goralski, Lindsay Meyerdirk, L Breton, L. Brasseur, Kevin Kurgat, Daniella DeWeerd, Lisa Turner, Katelyn Becker, Marie Adams, Daniel Newhouse, Michael X. Henderson

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Vol: 15

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Publication Date: 2024-03-26

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DOI - Digital Object Identifier: 10.1038/s41467-024-47027-8

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The oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling, and therapeutic implications

2024

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Title: The oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling, and therapeutic implications

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Publisher: Cold Spring Harbor Laboratory

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Publication Date: 2024-03-26

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DOI - Digital Object Identifier: 10.1101/2024.03.21.24304693

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[3H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain

2024

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Title: [3H]-NFPS binding to the glycine transporter 1 in the hemi-parkinsonian rat brain

Author(s): Imane Frouni, Esther Kim, Judy Shaqfah, Dominique Bédard, Cynthia Kwan, Sébastien Belliveau, Philippe Huot

Journal Name: Experimental Brain Research

Publisher: Springer Science and Business Media LLC

Vol: 242

Issue #: 5

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Publication Date: 2024-03-25

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DOI - Digital Object Identifier: 10.1007/s00221-024-06815-w

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