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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Resource: Utilizing DATATOP Biospecimens, 2014
    Circulating microRNAs as Progression Biomarkers for Parkinson's Disease

    Promising Outcomes of Original Grant:
    Our earlier study tested whether Parkinson’s disease (PD)-specific microRNAs in blood can be used to: (a) monitor disease development and (b) separate patients...

  • Access to Data and Biospecimens, 2014
    BDNF Polymorphism and Parkinson’s Disease Progression in DATATOP

    Study Rationale:
    A relatively common mutation in the brain derived neurotrophic factor (BDNF) gene exists in the human population. Neurotrophic factors are like brain fertilizers that help neurons grow...

  • Biomarkers Across Neurodegenerative Diseases, 2014
    Interpreting Disease Heterogeneity in Alzheimer’s and Parkinson’s Disease

    Study Rationale:
    The memory loss that is commonly associated with Alzheimer’s disease is thought to be caused by the accumulation of a protein called amyloid that disrupts the structure and function of...

  • Biomarkers Across Neurodegenerative Diseases, 2014
    Brain Networks as Targets of Neurodegeneration in Parkinson’s and Alzheimer’s Diseases

    Study Rationale:                   
    The study is based on two recent discoveries in neuroscience: (1) the brain is organized in large scale neuronal networks; (2) the misfolded proteins implicated in...

  • Biomarkers Across Neurodegenerative Diseases, 2014
    Cortical and Functional Distinctions in Alzheimer’s and Parkinson’s Diseases

    Study Rationale:
    Alzheimer’s disease (AD) and Parkinson’s disease (PD) are clinically distinct disorders, but their pathologies overlap considerably. Understanding how these overlaps relate to the two...

  • Research Grant, 2014
    Detection of Alpha-Synuclein Oligomers for the Diagnosis of Parkinson's Disease

    Study Rationale:                   
    Parkinson's disease (PD) is associated with the presence of protein aggregates in the form of Lewy bodies composed of the protein alpha-synuclein. One of the...

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