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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Target Validation, 2014
    Transferrin Receptor 2 as a Target to Halt Iron Overload in Parkinson's Disease

    Objective/Rationale:             
    Iron is an element naturally present in the brain and is required for its proper function. Iron levels, however, must be tightly controlled because excessive amounts...

  • Research Grant, 2014
    Phase IIb Study of Intranasal Glutathione in Parkinson’s Disease

    Study Rationale:                   
    The loss of the antioxidant glutathione in the brain of individuals with Parkinson’s disease (PD) occurs years before the onset of motor symptoms. Glutathione has...

  • Target Validation, 2014
    Inhibition of a Dopamine Receptor in Lymphocytes as a Treatment for Parkinson's Disease

    Objective/Rationale:             
    Emerging evidence has shown that lymphocytes, a kind of immune system cells, play a fundamental role in the development and progression of Parkinson's diseases. Our...

  • Research Grant, 2014
    Accelerated Pre-clinical Development of a Novel and Specific Alpha-synuclein Tracer

    Objective/Rationale:
    Biomarkers that can communicate the underlying pathology of Parkinson’s disease (PD) in living patients would be invaluable for diagnosis and for evaluation of disease-modifying...

  • Cognition Biomarkers, 2014
    miRNA Markers of Cognition

    Objective/Rationale:
    In previous MJFF-funded research, these researchers identified four promising microRNAs (which regulate gene expression) associated with cognitive status. They profiled the miRNAs...

  • Parkin Biology, 2014
    Role of Parkin in Innate Immunity

    Objective/Rationale:
    The protein Parkin contributes to the elimination of damaged mitochondria by a process called mitophagy. Prior research has shown that silencing Parkin gene affects innate immunity...

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Our funding programs support basic, translational and clinical research from academia and industry.

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