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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2017
    Radioactive Molecules for Detection of Alpha-synuclein and Amyloid-beta in the Brain

    Study Rationale:
    We will develop radioactive alpha-synuclein and beta-amyloid tracers -- molecules that allow researchers and clinicians to detect these two proteins in the brain using imaging...

  • Access to Data & Biospecimens, 2017
    Klotho and Parkinson’s disease

    Study Rationale:                   

    Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...

  • Access to Data & Biospecimens, 2018
    Rapid and Ultra-sensitive Quantitation of Disease-associated and Synuclein Seeds in Brain and Cerebrospinal Fluid by Syn RT-QuIC

    Study Rationale:                   

    The diagnosis and treatment of Parkinson’s disease (PD) would be aided by the availability of direct and highly sensitive tests for the abnormal clusters of the...

  • Access to Data & Biospecimens, 2015
    Evaluation of Alpha-synuclein and Hemoglobin Levels in CSF, Plasma and Saliva samples from the BioFind Cohort

    Study Rationale:                   

    Alpha-synuclein pathology plays a major role in Parkinson’s disease (PD). Recent studies suggest that measurement of alpha-synuclein in biological fluids (e.g...

  • Access to Data & Biospecimens, 2015
    NeuroX profiling of samples from the PPMI prodromal and genetic cohorts, the LRRK2 cohort consortium and the BioFIND cohort

    Study Rationale:                   

    This work aims to provide genetic information at common genetic variants and rare genetic variants that have been associated with Parkinson disease. To do this...

  • Access to Data & Biospecimens, 2015
    Whole Genome Sequencing and Analysis of the PPMI Prodromal and Genetic Cohorts, PPMI Genetic Registry and the LRRK2 Cohort Consortium

    Study Rationale:                   

    This work aims to provide genetic information for the whole genome and assess the role of the identified genetic information in Parkinson disease. To do this...

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