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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

  • California
  • 4

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  • LRRK2 Biology Consortium, 2017
    Describing the Structure and Function of LRRK2

    Study Rationale:
    Although leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD), little is known about its structure and function. To better...

  • Research Grant, 2017
    Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin

    Promising Outcomes of Original Grant:
    Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the...

  • Computational Science, 2017
    International Study of Parkinson's-related Changes in Brain Pathways Using Imaging Technique

    Study Rationale:
    Because Parkinson's disease (PD) affects people around the world regardless of their ethnicity or place of residence, research to find a cure for Parkinson's is truly an international...

  • Research Grant, 2017
    T Cell-mediated Autoimmune Responses in Parkinson's Disease

    Study Rationale
    The protein alpha-synuclein, which is misprocessed in nearly every case of Parkinson's disease (PD), forms the Lewy bodies seen in PD patient brain. In our recent MJFF-funded study, our...

  • PPMI Data Challenge, 2016
    Multivariate Prediction of Parkinson's Disease Clinical Progression (2016 PPMI Data Challenge Winner)

    Study Rationale:
    Parkinson's disease (PD) is heterogeneous in both clinical representation and prognosis, as indicated by a large diversity of rates of progression in motor as well as non-motor...

  • Improved Biomarkers and Clinical Outcome Measures, 2016
    Identification of Tear Biomarkers for Individuals with Parkinson's Disease

    Study Rationale:
    Prior to the appearance of classic movement abnormalities like tremor and slowness, those with Parkinson's suffer from non-motor symptoms, such as altered function of the...

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