The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Filter Results (17)
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Research Grant, 2018The Role of CD163 in Parkinson's Disease
Study Rationale:
Using pre-clinical models of Parkinson' disease (PD), we found CD163-positive macrophages -- immune cells with the CD163 protein on their surface -- to play an active role in... -
Research Grant, 2017Studying Alpha-synuclein Oligomers Using Oligomer-binding Antibodies
Study Rationale:
Alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), has long been implicated in the development of PD. Alpha-synuclein clumps vary in... -
Research Grant, 2017Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease
Study Rationale:
It is well known that the alpha-synuclein protein clumps in the cells of people with Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in... -
Therapeutic Pipeline Program, 2016Targeting Nicotinic Receptors to Increase Dopamine Function in Parkinson's Disease
Study Rationale:
Nicotinic alpha-6-containing receptors are a specific type of nicotinic receptor (proteins that respond to chemical messengers) expressed on dopamine neurons and are important... -
Dyskinesia Challenge, 2015Biomarkers and Sensors for Levodopa-induced Dyskinesia
Study Rationale:
Levodopa is the gold-standard drug for treatment of Parkinson’s disease (PD), but chronic use is associated with serious motor complications called levodopa-induced... -
Research Grant, 2014CD163+ Macrophages as Tools for Neuroinflammatory Modulation in Parkinson’s Disease Supplement
Promising Outcomes of Original Grant:
Our fundamental hypothesis was that modulation of blood CD163+ macrophages using nanoparticles loaded with anti-inflammatory drugs could protect neurons in the...

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Our funding programs support basic, translational and clinical research from academia and industry.