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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

  • Denmark

Filter Results (17)

  • Research Grant, 2018
    The Role of CD163 in Parkinson's Disease

    Study Rationale:
    Using pre-clinical models of Parkinson' disease (PD), we found CD163-positive macrophages -- immune cells with the CD163 protein on their surface -- to play an active role in...

  • Research Grant, 2017
    Studying Alpha-synuclein Oligomers Using Oligomer-binding Antibodies

    Study Rationale:
    Alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), has long been implicated in the development of PD. Alpha-synuclein clumps vary in...

  • Research Grant, 2017
    Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease

    Study Rationale:
    It is well known that the alpha-synuclein protein clumps in the cells of people with Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in...

  • Therapeutic Pipeline Program, 2016
    Targeting Nicotinic Receptors to Increase Dopamine Function in Parkinson's Disease

    Study Rationale:
    Nicotinic alpha-6-containing receptors are a specific type of nicotinic receptor (proteins that respond to chemical messengers) expressed on dopamine neurons and are important...

  • Dyskinesia Challenge, 2015
    Biomarkers and Sensors for Levodopa-induced Dyskinesia

    Study Rationale:                   
    Levodopa is the gold-standard drug for treatment of Parkinson’s disease (PD), but chronic use is associated with serious motor complications called levodopa-induced...

  • Research Grant, 2014
    CD163+ Macrophages as Tools for Neuroinflammatory Modulation in Parkinson’s Disease Supplement

    Promising Outcomes of Original Grant:
    Our fundamental hypothesis was that modulation of blood CD163+ macrophages using nanoparticles loaded with anti-inflammatory drugs could protect neurons in the...

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