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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Computational Science, 2017
    Analyzing Data from the Parkinson’s Progression Markers Initiative to Identify Subtypes of Parkinson’s Disease

    Study Rationale:
    Parkinson's disease (PD) presents and progresses variably, so no two people with Parkinson's have the same disease. The diversity of PD clinical manifestations makes the disease more...

  • Computational Science, 2017
    Complex Data Analysis for the Development of Parkinson’s Disease Biomarkers

    Study Design:
    To test this hypothesis, we will employ recent discoveries in computer science, PD biomarker research and standardized sets of PD data. First, we will develop machine-learning techniques...

  • Therapeutic Pipeline Program, 2017
    Alternative Brain Stimulation Approach for the Treatment of Swallowing Impairment in Parkinson’s Disease

    Study Rationale:
    Dysphagia -- difficulty swallowing -- is common in people with advanced Parkinson's disease (PD). Dysphagia often leads to aspiration -- inhaling of food -- which can result in...

  • Target Advancement Program, 2017
    Synapsin III as a Novel Therapeutic Target in Parkinson's Disease

    Promising Outcomes of Original Grant:
    Although the role of alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), is not entirely clear, it is believed to...

  • Research Grant, 2017
    A Study of Gastrointestinal Impairment in Parkinson's Disease

    Study Rationale:
    Gastrointestinal (GI) symptoms, such as constipation, nausea and vomiting, are common in Parkinson's disease (PD), but the cause of these symptoms is not entirely clear. Slow movement...

  • Research Grant, 2017
    Studying Alpha-synuclein Oligomers Using Oligomer-binding Antibodies

    Study Rationale:
    Alpha-synuclein, the sticky protein that clumps in the cells of people with Parkinson's disease (PD), has long been implicated in the development of PD. Alpha-synuclein clumps vary in...

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