The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Target Advancement Program, 2016Role of Inflammation in Parkinson's Disease
Hypothesis:
We hypothesize that the inflammatory protein galectin-3 contributes to PD progression.Study Design:
We will use pre-clinical models that lack galectin-3 to evaluate inflammation, neuronal... -
Research Grant, 2016Parkinson's Disease Research Database
Study rationale:
Advances in our understanding of the genetics of Parkinson's disease (PD) have led to the generation of an array of pre-clinical models that mimic various hallmarks of the disease... -
Research Grant, 2016Identification of Genetic Signatures in the Blood as Biomarkers for Parkinson's Disease
Study Rationale:
Epigenetic processes (changes in gene expression), such as DNA methylation (mechanism that cells use to control gene expression), ensure proper functioning of genetic materials in... -
Therapeutic Pipeline Program, 2016Targeting Nicotinic Receptors to Increase Dopamine Function in Parkinson's Disease
Study Rationale:
Nicotinic alpha-6-containing receptors are a specific type of nicotinic receptor (proteins that respond to chemical messengers) expressed on dopamine neurons and are important... -
Research Grant, 2016Rab Detection Initiative
Study Rationale:
The LRRK2 enzyme regulates proteins through a process called phosphorylation. The LRRK2 gene, which is mutated in familial Parkinson's disease (PD), an inherited form of PD, can... -
Target Advancement Program, 2016Protecting Dopamine Neurons in Parkinson's Disease
Study Rationale:
Parkinson's disease (PD) is caused by death of dopamine-containing cells in the brain. We discovered that a protein known as RGS6 is expressed in these cells in pre-clinical models of...
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Our funding programs support basic, translational and clinical research from academia and industry.