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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    Pathogenesis of the Virome in Parkinson’s Disease

    Study Rationale:
    Numerous studies have implicated viruses as causal factors or potential triggers for Parkinson’s disease (PD). Our study will provide a comprehensive understanding of all the viral...

  • Astrocyte Biology in Parkinson's Disease, 2019
    Astrocyte Gene Expression in Parkinson’s Interrogated Using Single Cell Nuclear RNA Sequencing

    Study Rationale:
    Astrocytes are one of the major non-neuron cell types in the brain and control many neurological processes. They are likely to be changed in Parkinson’s disease (PD) and may...

  • MJFF Research Grant, 2013
    Specific Modulation of Tau Oligomers by Passive Immunotherapy in a Parkinson's Disease Model

    Objective/Rationale: 
    The accumulation of tau protein is an important pathogenic factor in Parkinson’s disease (PD) and other neurodegenerative disorders. Our recent findings from pre-clinical models...

  • MJFF Research Grant, 2012
    Novel PD Tools: Generation of Posttranslationally Modified Alpha-synuclein

    Objective/Rationale:             
    There is increasing evidence linking specific posttranslational modification (folding, cutting, etc. of proteins before maturation) and alpha-synuclein aggregation...

  • LRRK2 Challenge, 2013
    In Vivo Rescue of Dopamine Release Deficits via Kinase Inhibition in LRRK2 Mutant Mice

    Objective/Rationale:             
    Abnormal kinase activity is thought to be responsible for the pathogenic effects of LRRK2 in parkinsonian patients and many lines of evidence point towards a role of...

  • Research Grant, 2013
    Validation of Blood-borne Autoantibody Biomarkers for Parkinson’s Disease Supplement

    Promising Outcomes of Original Grant:
    The purpose of the original study was to determine if a small group of selected blood-borne autoantibody biomarkers that were previously shown to be effective in...

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Our funding programs support basic, translational and clinical research from academia and industry.

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