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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2024
    Determining Optimal Cognitive Measures and Clinical Trial Endpoints in Lewy Body Disorders

    Study Rationale: People with Lewy body disorders, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), often experience cognitive impairment that can impact function, independence...

  • , 2024
    Epigenetic Analysis of Peripheral Immunity in Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) has increasingly been linked to dysfunction in the immune system, with evidence showing abnormal activity in blood immune cells and their potential role in...

  • ASAP CRN Competitive Renewal Opportunity, 2025
    Examining the Dual Role of Neural Activity in Parkinson’s Disease
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    Study Rationale: Most previous work on brain circuitry in Parkinson’s disease (PD) has focused on what happens after the loss of dopamine neurons. However, we know that changes in the function of...

  • iPSC Phenotyping Environmental Exposure Program, 2024
    Using Stem-cell Derived Brain-chip Technologies to Evaluate the Contributions of Environmental Toxins to Parkinson’s Disease

    Study Rationale: Chronic exposure to environmental contaminants is believed to play an important role in the initiation of Parkinson’s disease (PD). With an estimated 40,000 to 60,000 chemicals that...

  • Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025
    Investigating the Mechanisms of Alpha-synuclein-induced Anxiety in a Novel Preclinical Model of Parkinson’s Disease

    Study Rationale: Although Parkinson’s disease (PD) is known as a movement disorder, non-motor symptoms like anxiety can severely reduce individuals’ quality of life. Unfortunately, we know very little...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Identifying Biomarkers for the Common Mechanism Underlying the Disease Continuum from Parkinson’s Disease to Alzheimer’s Disease

    Study Rationale: Disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) share many similarities in their pathology. In particular, both involve accumulation of amyloid-β and alpha...

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