The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP, 2023(SUPPLEMENT) Using Single-cell Analyses to Understand Inherited and Acquired Genetic Variation in Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) is a disorder that not only affects the function of the brain, but also the gut. Both of these are complex tissues composed of functionally diverse cell types...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Targeting the Blood-brain Immune Axis to Prevent Progression of Parkinson’s Disease
Study Rationale: Recent studies suggest that the barrier that separates the brain from the rest of the body, including the blood, might become dysfunctional over the course of Parkinson’s disease (PD)...
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Lysosomal Biomarkers Program, 2023Investigating the Role of Lysosomal Biomarker ATP13A2 in the Pathogenesis of Parkinson’s Disease
Study Rationale: Lysosomal impairment is strongly implicated in the pathology of Parkinson’s disease (PD). Loss-of-function mutations in ATP13A2, a gene that encodes a lysosomal protein, are causally...
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Research Grant, 2023(SUPPLEMENT) The Foundational Data Initiative
Study Rationale: This project aims to produce foundational data that will provide a resource for understanding the molecular basis of Parkinson’s disease (PD). The work, conducted in cells collected...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Examining a Novel GCase Activator in Neurons Derived from People with Parkinson’s Disease
Study Rationale: Decreased function of the lysosomal enzyme GCase is associated with Parkinson’s disease (PD). We discovered that LIMP-2, the protein that transports GCase to the lysosome, also...
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Research Grant, 2023(SUPPLEMENT) Development of an Imaging Tracer for Measuring Alpha-synuclein
Study Rationale: The discovery of new treatments for Parkinson’s disease (PD) has been hampered by the amount of time it can take (typically a number of years) to determine whether a drug works in a...
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Our funding programs support basic, translational and clinical research from academia and industry.