The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021Characterization of PET Tracers for Alpha-synuclein and 4R Tau
Study Rationale:
Parkinson’s disease (PD) is a brain disease characterized by slow movement, rest tremor and stiffness. In most cases the underlying cause is an aggregation of a protein called alpha... -
Target Advancement Program, 2021Pathogenic Mechanisms for Auxilin-mediated Parkinson's Disease
Study Rationale:
Parkinson’s disease (PD) is a prevalent neurodegenerative movement disorder. Several genetic mutations that cause PD have been identified in patients. One such mutation targets... -
Therapeutic Pipeline Program, 2021Proof of Concept and Translational Validation of USP30 to Offset Dysfunction in the PRKN Pathway
Study Rationale:
USP30 is an enzyme which acts in the opposite way to Parkin (PRKN), a gene linked to young-onset Parkinson’s disease (PD). Mutations in the PRKN gene impact mitochondria (the cell’s... -
Therapeutic Pipeline Program, 2021Understand Me for Life: An Intelligibility App for Parkinson's Disease
Study Rationale:
Approximately 90% of people with Parkinson’s develop speech and language problems over the course of the disease, and more than half of these speakers experience problems with... -
Therapeutic Pipeline Program, 2021Dietary Interventions to Slow and Improve Parkinson’s Symptoms by Restructuring the Gut Microbiome and Decreasing Inflammation
Study Rationale:
There is a link between the gut and the brain in Parkinson’s disease (PD), and gut bacteria may play an important role. Gut bacteria they affect the bowel mucus barrier, produce... -
Research Grant, 2021Hypoxia (Limiting Oxygen Levels) as a Novel Treatment for Parkinson’s Disease
Study Rationale:
Many anecdotes suggest that people with Parkinson’s disease (PD) can experience a marked improvement in symptoms when they travel to the mountains or during flights at high altitude...
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Our funding programs support basic, translational and clinical research from academia and industry.