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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2021
    Pharmacological Targeting of Inflammation to Modify Disease Progression in Pre-clinical Models of Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by pronounced brain inflammation. Despite being the most common movement disorder to date, no therapy...

  • Therapeutic Pipeline Program, 2021
    Development of Compounds that Destroy Alpha-Synuclein Aggregates for the Treatment of Parkinson’s Disease

    Study Rationale:
    Multiple lines of evidence indicate that alpha-synuclein forms aggregates similar to those adopted by infectious prion proteins, and that these toxic clusters are responsible for the...

  • Biomarkers, 2021
    Use of Neuronal Exosomes to Predict Parkinson’s Disease

    Study Rationale:
    In Parkinson’s disease (PD), the build-up of alpha-synuclein inside nerve cells leads to formation of abnormal clumps and death of dopamine-producing cells and other neurons. By the...

  • Environmental Risk Factors, 2021
    Exposure to Ambient Air Pollution and Risk of Parkinson’s Disease

    Study Rationale:
    Ambient (outdoor) air pollution can increase the risk of cardiovascular diseases and death. Some evidence links ambient air pollution to higher risk of Parkinson’s disease. But...

  • Environmental Risk Factors, 2021
    Nationwide Geographic Cluster Analysis of Incident Parkinson’s Disease

    Study Rationale:
    The causes of Parkinson’s disease (PD) are mostly unknown, but non-genetic factors, such as environmental exposures during one’s lifetime, probably affect whether a person develops PD...

  • Research Grant, 2022
    Evaluation of a Monitoring System Based on a Wearable Sensor for Improving Swallowing and Saliva Control in Parkinson’s Disease

    Study Rationale: Trouble with swallowing and increased drooling are common issues for people with Parkinson’s disease (PD). These oral symptoms occur in up to 80% of cases. Our prior work showed that...

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