The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Community Fast Track, 2003Regulation of Dopaminergic Pathways by Eph Family Receptors
Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...
-
Fast Track, 2001Synuclein, Parkinson's Disease and Strategies for Neuroprotection
Parkinson's disease results from a loss of dopamine neurons in brain areas that control body movement. However, the cause of this loss is unknown and thus it has been difficult to develop rational...
-
The Role of Protein Degradation in Parkinson's Disease, 2002RNAi Screening and Analysis of Factors Influencing ER-Associated Degradation and Alpha-Synuclein Aggregation in C. elegans
Failure of proteins to adopt their proper structure is a common cause of cellular dysfunction. Quality control mechanisms within cells serve to promote accurate protein folding. Breakdown of these...
-
The Role of Protein Degradation in Parkinson's Disease, 2002Lentiviral Mediated Effect of Chaperones & Parkin in a Genetic Model of Parkinson's disease
The study of familial Parkinson disease indicates that the loss of nerve cells of a brain structure named the substantia nigra may be related to the accumulation of proteins aggregating within these...
-
The Role of Protein Degradation in Parkinson's Disease, 2002Regulation of Nurr1 Nuclear Receptor Transcriptional Activity by the Ubiquitin Proteasome System
Parkinson's disease (PD) is a neurodegenerative disease involving progressive and selective death of dopamine producing neurons located in the midbrain. Survival and normal activity of these neurons...
-
The Role of Protein Degradation in Parkinson's Disease, 2002Parkin-Mediated Ubiquitination at the Synapse
Parkinson's disease (PD) involves the death of dopamine neurons in the midbrain and leads to devastating motor and functional impairment. Although treatment is available, its effectiveness diminishes...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.