The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Parkinson’s Disease Therapeutics Pipeline Program, 2025Late-preclinical Development of a Differentiated TRPML1 Agonist to Slow Progression of Parkinson’s Disease
Study Rationale: TPRML1 is protein found on lysosomes, which serve as the cell’s degradation and recycling center. Lysosomes stop working properly in Parkinson’s disease and accumulate garbage...
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T2T Validation - Endolysosomal Targets, 2025Development of Translational Biomarkers for TRPML1 Target Engagement in Intact Whole Human Parkinson’s Disease Brains
Study Rationale: TRPML1 is a promising drug target that offers the potential to slow the course of Parkinson’s disease. This study utilizes Bexorg’s revolutionary postmortem human brain platform to...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025SNP614, A LRRK2 Antisense Oligonucleotide as Potential Therapeutic Agent for Parkinson's Disease
Study Rationale: Parkinson’s disease (PD) is estimated to affect as many as 1 million Americans and up to 10 million people worldwide. The exact cause of PD is not yet fully understood, and currently...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025Biomarker and IND-enabling Studies to Advance a CNS Penetrant GCase Activator for the Treatment of Parkinson’s Disease
Study Rationale: The complexity of Parkinson’s disease (PD) has contributed to the poor success rate in drug development. At Neumora we seek to understand this complexity by identifying the biological...
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Research Grant, 2025Powered Clothing and Wearable Robotics for Improved Gait, Balance and Reduced Freezing in Everyday Life
Study Rationale: We’ve spent several years exploring the potential of supporting human movement with wearable robotics and we believe it has tremendous potential for the Parkinson’s community. With...
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Research Grant, 2025A Comparative Performance Study between High and Standard Resolution Positron Emission Tomography Camera using [18F]AV-133 in Prodromal Parkinson’s Disease [Dual PET AV133 in Prodromal PD]
Study Rationale: Parkinson’s disease (PD) is characterized by a prodromal phase long before someone presents with the clinical features of PD. During this phase, there are progressive biological...
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Our funding programs support basic, translational and clinical research from academia and industry.