The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Using Deep Learning to Evaluate Changes Associated with Parkinson’s Disease
Study Rationale:
Recent advances in artificial intelligence and, in particular, in one of its methods called deep learning offer exciting opportunities for the diagnosis and treatment of Parkinson’s... -
Research Grant, 2018Developing TLR2-Blocking Drugs to Reduce Alpha-synuclein-Induced Inflammation in Parkinson's Disease
Promising Outcomes of Original Grant: 100 words)
Synucleinopathies, including Parkinson's disease (PD), is a group of disorders affecting the central nervous system (CNS). These disorders share one key... -
Research Grant, 2018Examining GCase Activity in People with REM Sleep Behavior Disorder
Study Rationale:
Approximately 80 percent of people with REM sleep behavior disorder (RBD) will develop a neurological disorder such as Parkinson's disease (PD). GBA mutations are the most frequent... -
Research Grant, 2018Studying GBA Pseudogene as a Controller of GBA and Alpha-synuclein
Study Rationale:
Mutations (changes) in the GBA gene are the most common genetic risk factor for Parkinson’s disease (PD). GBA has a clone called pseudogene, a similar stretch of DNA that, unlike the... -
GBA Biology and Therapies, 2018Link between LRRK2 Activity and Glucocerebrosidase Deficits in Idiopathic Parkinson’s Disease
Study Rationale:
Earlier work from this group reported greater LRRK2 activity in people with idiopathic (cause unknown) Parkinson’s. This project builds on those findings to investigate how that... -
GBA Biology and Therapies, 2018Analyzing Genetic Modifiers Using a CRISPR Activation/Inhibition GBA-PD Model
Study Rationale:
Clinical and genetic studies show that mutations in the GBA gene are risk factors for developing Parkinson’s disease (PD) and lead to an accumulation of glycolipids in the lysosome...
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Our funding programs support basic, translational and clinical research from academia and industry.