The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Diversity, Equity and Inclusivity in Parkinson's research, 2022Parkinson’s Disease in Southern Africa
Study Rationale: Most studies on Parkinson’s disease (PD) are focused on patients in Europe and North America. It is crucial to investigate patterns and the causes PD in other parts of the world. It...
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2022: Accelerated Therapeutics Program, 2022Preclinical and Early Clinical Development of NPT1220-478 for the Treatment of Parkinson's Disease
Study Rationale: Parkinson’s disease is a progressive neurodegenerative disorder; meaning that from its inception, neurons are continuously dying with resulting worsening of neurologic symptoms. Two...
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Fall 2020 RFA: Therapeutic Pipeline Program-Pre-Clinical, 2022Targeting Colony-stimulating Factor 1 Receptor (CSF1R) to Modify Disease Progression in Preclinical Experimental Models of Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by pronounced neuroimmune dysfunction. Although the disease is very common, no therapy is available...
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Research Grant, 2022Objectively Measuring the Severity of Vocal and Speech-related Symptoms Associated with Parkinson’s Disease
Study Rationale: The ability to objectively measure vocal symptoms is necessary to better characterize the emergence and development of speech deficits, particularly in the early phases of Parkinson’s...
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2022: Accelerated Therapeutics Program, 2022Using Small Molecules that Modulate Mitochondrial Function for the Treatment of Parkinson's Disease
Study Rationale: Dysfunction in energy-producing structures called mitochondria is a crucial driver of the initiation and progression of Parkinson’s disease (PD). Mitochondria in the cells of people...
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Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022Assessment of Alpha-synuclein Aggregation Inhibitor ASN121151 as a Potential New Treatment for Parkinson’s Disease
Study Rationale: Genetic defects in the gene encoding alpha-synuclein cause the protein to aggregate in the brains of people with a familial form of Parkinson’s disease (PD). We have developed a novel...
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Our funding programs support basic, translational and clinical research from academia and industry.