The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Parkinson’s Disease Therapeutics Pipeline Program, 2024Examining the Effects of MTX325 on Mitochondrial Quality Control and the Prevention of Parkinson’s Disease Progression
Study Rationale: Mitochondria generate the energy needed for cells to work properly, and impaired mitochondrial function has been linked to the loss of dopamine neurons in multiple forms of Parkinson...
-
Parkinson’s Disease Therapeutics Pipeline Program, 2024Use of an Angiotensin-(1-7) Glycopeptide, to Treat Dementia in Parkinson's Disease
Study Rationale: Peptide-based drugs are attractive candidates for treating the cognitive decline associated with Parkinson’s disease (PD) because they demonstrate a robust safety profile and an...
-
[RFA] Use of PD Biosamples - Spring 2020, 2024Neurotoxic Inflammatory Metabolites as Biomarkers of Disease Progression in Parkinson’s Disease
Study Rationale: Individuals with Parkinson’s disease (PD) have inflammation in the brain, cerebrospinal fluid and the blood. We think that inflammation drives the worsening of PD because it increases...
-
Research Grant, 2024Chronos-PD Pilot: Analyzing Plasma from Donors Who Develop Parkinson’s Disease Later in Life
Study Rationale: Our current molecular understanding of Parkinson’s disease (PD) is based on the clinical phase of the disease. However, because PD is a progressive disease, by the time the disorder...
-
Research Grant, 2024Developing a Binding Assay to Detect Toxic Alpha-synuclein Aggregates in Cerebrospinal Fluid and Plasma
Study Rationale: The formation of toxic protein aggregates is an early step in the pathology of several neurodegenerative disorders, including Parkinson’s disease (PD). Using computer simulations, we...
-
Research Grant, 2024(SUPPLEMENT) Investigation of Small Molecules for Rescuing Lysosomal and GBA1 Deficiencies in GBA-associated Parkinson’s Disease
Study Rationale: Individuals with mutations in the GBA1 gene encoding the enzyme β-glucocerebrosidase (GCase) have a higher risk of Parkinson’s disease (PD). Gaucher disease, a rare genetic disease...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.