The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2025The BioFINDER Studies: Identifying Disease Stages and Effects of Co-morbidities in Neuronal Synuclein Disease
Study Rationale: Neuronal synuclein disease (NSD) is the underlying cause of Parkinson’s disease (PD) and similar disorders. Recently, new tests have allowed us to measure signs of NSD before symptoms...
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Spring 2022 RFA: Therapeutic Pipeline Program Pre-Clinical, 2024Exploring Paxalisib as a Novel Therapeutic for Parkinson’s Disease
Study Rationale: Studies in preclinical models of Parkinson’s disease (PD) and in postmortem PD brains suggest that a signaling pathway that is switched on by activation of a protein called...
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ASAP CRN Competitive Renewal Opportunity, 2024Investigating How Alpha-synuclein-rich Neurons in Olfactory Circuits Respond to Environmental Triggers at the Initiation of Parkinson Disease
Study Rationale: To slow the progression of Parkinson disease (PD), we need to understand how, where and why the illness starts. It is estimated that most individuals with PD experience a significant...
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iPSC Phenotyping Environmental Exposure Program, 2025Assessing How Triplication of the Alpha-synuclein Gene Affects Electrophysiological and Mitochondrial Phenotypes in Neurons, Astrocytes and Microglia
Study Rationale: One common familial inherited form of Parkinson’s disease (PD) is caused by triplication of SNCA, the gene that encodes the protein alpha-synuclein. Alpha-synuclein forms toxic...
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Research Grant, 2024Determining Optimal Cognitive Measures and Clinical Trial Endpoints in Lewy Body Disorders
Study Rationale: People with Lewy body disorders, including Parkinson’s disease (PD) and dementia with Lewy bodies (DLB), often experience cognitive impairment that can impact function, independence...
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, 2024Epigenetic Analysis of Peripheral Immunity in Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) has increasingly been linked to dysfunction in the immune system, with evidence showing abnormal activity in blood immune cells and their potential role in...
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Our funding programs support basic, translational and clinical research from academia and industry.