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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Cell Line, 2002
    Banking of and Dopamine Neuronal Production from Human Neural Stem Cells

    Transplantation of dopamine neurons in Parkinson's disease has resulted in significant improvements for some patients. However, large-scale clinical trials are impossible due to the technical and...

  • Cell Line, 2002
    Generation of Transplantable Dopamine Neurons from Human Emryonic Stem Cells

    The focal nature of neuronal loss suggests that cell replacement therapy may be suitable for Parkinson's disease. Indeed, transplanted fetal midbrain cells survive in some Parkinson's patients for...

  • Fast Track, 2001
    Lentiviral Delivery of Neublastin to MPTP-Treated Pre-clinical models

    Parkinson's disease (PD) results primarily from striatal dopamine (DA) insufficiency and degeneration of dopaminergic neurons within the substantia nigra pars compacta. The cause of PD still remains...

  • Fast Track, 2001
    Rapid Parkinson's Drug Screen Using Parkin Knockout Stem Cells

    Autosomal recessive loss-of-function mutations in the parkin gene are the most common cause of familial Parkinson's disease (PD), which is characterized by selective loss of dopaminergic (DA) neurons...

  • Fast Track, 2001
    PET Neuroimaging Study of the Brain Serotonin Transporter in Parkinson's Disease: Relationship to Clinical Depression

    Approximately 40% of patients with Parkinson's disease (PD) suffer from depression, which in many cases is more disabling than the impairment of motor function. Since the original discovery by Oleh...

  • Fast Track, 2001
    Generation and Analysis of Conditional Pre-Clinical Model Mutants for BNDF and GDNF Receptors

    Parkinson's disease results largely from the degeneration of dopamincergic neurons in the substantia nigra pars compacta. The reason for the successive death of these neurons is not known so far...

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