The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Fast Track, 2001Efficient Generation and Transplantation of Dopamine Neurons Derived from Cloned Pre-Clinical Model Embryonic Stem Cells
In previous work, we have successfully generated functional dopamine neurons from both fetal CNS- and embryonic stem cells in animals. More recently (in collaboration with Rockefeller University) we...
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Fast Track, 2001Multipotent Stem Cell Therapy for Parkinson's Disease
We have identified stem cells in post-natal marrow of humans and animals that can be induced to differentiate at the clonal level to cells of mesodermal, neuroectodermal, and endodermal origin...
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Fast Track, 2001Functional Consequences of Glutathione-Mixed Disulfide Formation in Brain Mitochondria
Glutathione depletion and mitochondrial defects have been implicated in the etiology of Parkinson's disease (PD). Our previous work examined the cellular mechanisms underlying dopamine cell loss in...
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Community Fast Track, 2003Regulation of Dopaminergic Pathways by Eph Family Receptors
Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...
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Fast Track, 2001Synuclein, Parkinson's Disease and Strategies for Neuroprotection
Parkinson's disease results from a loss of dopamine neurons in brain areas that control body movement. However, the cause of this loss is unknown and thus it has been difficult to develop rational...
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The Role of Protein Degradation in Parkinson's Disease, 2002RNAi Screening and Analysis of Factors Influencing ER-Associated Degradation and Alpha-Synuclein Aggregation in C. elegans
Failure of proteins to adopt their proper structure is a common cause of cellular dysfunction. Quality control mechanisms within cells serve to promote accurate protein folding. Breakdown of these...
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Our funding programs support basic, translational and clinical research from academia and industry.