The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2012Novel PD Tools: Generation of Posttranslationally Modified Alpha-synuclein
Objective/Rationale:
There is increasing evidence linking specific posttranslational modification (folding, cutting, etc. of proteins before maturation) and alpha-synuclein aggregation... -
LRRK2 Challenge, 2013In Vivo Rescue of Dopamine Release Deficits via Kinase Inhibition in LRRK2 Mutant Mice
Objective/Rationale:
Abnormal kinase activity is thought to be responsible for the pathogenic effects of LRRK2 in parkinsonian patients and many lines of evidence point towards a role of... -
Research Grant, 2013Validation of Blood-borne Autoantibody Biomarkers for Parkinson’s Disease Supplement
Promising Outcomes of Original Grant:
The purpose of the original study was to determine if a small group of selected blood-borne autoantibody biomarkers that were previously shown to be effective in... -
Research Grant, 2013Six-month Oral Toxicity Study of the Accordion Pill™ of Carbidopa/Levodopa
Objective/Rationale:
The Accordion Pill™ is designated to significantly stabilize the pharmacokinetic profile of drugs with a narrow absorption window, such as levodopa. Regular controlled-release... -
Target Validation, 2012Validating Monoacylglycerol Lipase Inhibitors in Combatting Parkinson’s Disease
Objective/Rationale:
Chronic and persistent inflammation in the brain has been shown to be an underlying driver of Parkinson’s disease (PD). Anti-inflammatory strategies may be beneficial... -
Dyskinesia Challenge, 2012Evaluation of Cortical Resonant Oscillations as a Novel Target for Treatment of Dyskinesia
Objective/Rationale:
In our research we aim to identify changes in neuronal circuits that cause motor symptoms in Parkinson’s disease (PD) by recording neuronal activity in healthy and in...
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Our funding programs support basic, translational and clinical research from academia and industry.