The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2015GAITPARK_ATLAS: Finding New Targets to Treat Gait and Balance Disorders in Parkinson’s Disease
Study Rationale:
Gait and balance disorders are the primary motor disability in advanced Parkinson’s disease (PD). These disorders arise in part due to dysfunction of the lateral... -
Research Grant Supplement, 2015Parc (a Parkin-related E3 ligase): Functions in Neuronal Survival and Parkinson’s Disease Supplement
Promising Outcomes of Original Grant:
Our research had identified a Parkin-related protein, called Parc, to be important for neuronal survival in situations of mitochondrial injury. Specifically, we... -
Improved Biomarkers and Clinical Outcome Measures, 2015Measuring Altered White Blood Cell Functionality as a Biomarker of Parkinson’s Disease
Study Rationale:
White blood cells from people with Parkinson’s disease (PD) patients appear to differ from those of control individuals in that there are differences in the set of genes that are... -
Research Grant Supplement, 2015The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model Supplement
Promising Outcomes of Original Grant:
We hypothesized that that deposits of the Parkinson’s disease-associated protein alpha-synuclein in gut and brain neurons are caused by exposure to proteins of... -
Research Grant Supplement, 2015Modulation of MicroRNA Activities in Parkinson's Disease
Objective/Rationale:
Previous data support that small non-coding gene regulatory RNAs, known as microRNAs, are dysregulated in Parkinson’s disease (PD). However, the disease-relevance of these changes... -
Improved Biomarkers and Clinical Outcome Measures, 2015Method to Quantify Parkinsonian Motor Signs for Interventional Drug Trials
Study Rationale:
Current methods to evaluate motor impairments in Parkinson’s disease rely on subjective examinations. Our team seeks to develop an objective assessment of motor...
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Our funding programs support basic, translational and clinical research from academia and industry.