The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biomarkers, 2025Dried Blood Spot PNPO Activity as a Biomarker for the Stratification of Parkinson's Disease
Study Rationale: Parkinson’s disease starts much earlier than the signs appear and people seek diagnosis. Scientists are therefore searching for changes that are relevant to the disease that could be...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025Neuro-steroid Mediated Control of Sleep Co-morbidities in Parkinson's Disease
Study Rationale: Sleep disorders affect a large proportion of people with Parkinson’s disease (PD) and are often refractory to standard medications. Excessive daytime sleepiness (EDS), which is...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025CT600 as a Neuroprotective Peptide Therapeutic for Parkinson’s Disease
Study Rationale: Excess CDK5 protein kinase activity in the brain caused by the binding of CDK5 with another protein called P25 has been connected to Parkinson's disease. The CDK5-P25 interaction can...
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Research Grant, 2025Analysis of a Potential Alpha-synuclein PET Tracer (18F-FD4) in HC, PD and MSA
Study Rationale: 18F-FD4 is a new imaging agent that has the potential to image alpha-synuclein in the living human brain with Positron Emission Tomography (PET). Given alpha-synuclein’s central role...
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Research Grant, 2025Scamps: Endosomal Membrane Proteins that Control Alpha-synuclein Traffic
Study Rationale: Parkinson’s Disease progresses with the death of nerve cells in the brain. Some forms of the disease run in families due to mutations in important genes. One of these genes is called...
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MRI Biomarkers Program, 2025Validate Diffusion MRI Biomarkers of Early PD: A Multi-cohort Study of Free-water and CDM Measure
Study Rationale: Parkinson’s disease and related synucleinopathies, such as Dementia with Lewy Bodies, are challenging to diagnose at their earliest stages due to subtle initial symptoms. Our research...
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Our funding programs support basic, translational and clinical research from academia and industry.