The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Clinical Discovery Awards, 2006Workplace Exposures and Biomarkers of Parkinsonism in Welders
The etiology of Parkinson's disease is unknown although previous research has implicated environmental factors in most cases. We have previously shown that welding, an occupation performed by over 500...
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Clinical Discovery Awards, 2006Treating speech disorders in patients with Parkinson's disease using altered auditory feedback
Speech problems are common in patients with Parkinson's disease. At an early stage, patients may find it hard to project their voice. As the disease progresses, patients start to have difficulty...
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Community Fast Track, 2005Nigrostriatal Dopaminergic Degeneration and Alpha-synuclein Aggregation in Mice with Reduced TrkB Signaling
Parkinson's disease (PD) is characterized by progressive loss of dopaminergic neurons and deposition of cytoplasmic protein aggregates termed Lewy bodies (LB) in a brain structure termed substantia...
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Community Fast Track, 2005Pathophysiological Role of PINK1 in Rodent Brain
Mutations in the PINK1 gene were recently linked to autosomal recessive parkinsonism. However, to date, very little is known about the role of PINK1 in the brain. Our group has ample expertise with...
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Community Fast Track, 2005Novel Therapeutic Approaches for Parkinson ’s Disease
Our goal is to develop novel therapeutic agents for the treatment of Parkinson's disease. We will focus on two compounds. One of these blocks the mitochondrial permeability transition (MPT), which is...
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Community Fast Track, 2005Neoangiogenesis and Blood-Brain Barrier in L-DOPA-induced Dyskinesia
Fluctuations in brain levels of levodopa play a key role in the production of dyskinesia (abnormal involuntary movements) and motor fluctuations in Parkinson's disease. This project explores the...
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Our funding programs support basic, translational and clinical research from academia and industry.