The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2016Convergence of LRRK2 and GBA1 in the Pathogenesis of Parkinson's Disease
Study Rationale:
Genetic studies in Parkinson's disease (PD) have led to the discovery of several causal and risk genes, whose mutations contribute to some forms of PD; among those described are... -
Target Advancement Program, 2016Investigation of Lipid Metabolism in GBA-associated Parkinsonism
Study Rationale:
Genetic changes in the glucocerebrosidase (GBA) gene are linked to a higher risk of developing Parkinson's disease (PD) and dementia with Lewy bodies (DLB). These changes in GBA in... -
Improved Biomarkers and Clinical Outcome Measures, 2016Corneal Confocal Microscopy: A Novel Imaging Biomarker for Parkinson's Disease
Study Rationale:
We have pioneered a technique in which we can photograph nerves on the surface of the eye. This technique can be used to monitor the severity of various neurological conditions. In our... -
Target Advancement Program, 2016Assessing the Role of Glucosylceramide in Alpha-synuclein-induced Toxicity
Study Rationale:
Loss-of-function GBA1 mutations in Gaucher disease result in increased risk for Parkinson's disease (PD). Glucocerebrosidase (GCase) normally breaks down a lipid called... -
Target Advancement Program, 2016Assessing the PINK1 Pathway in Parkinson
Study Rationale:
Rare mutations in the PINK1 gene cause familial (inherited) Parkinson's disease (PD). However, it is not known if PINK1 contributes to the development of idiopathic (no known cause) PD... -
Research Grant, 2016Investigation of LRRK2 as a Regulator of Dendritic Cell Function
Promising Outcomes of Original Grant:
Myeloid cells (white blood cells) of the immune system include monocytes, neutrophils and dendritic cells found in circulation, as well as microglia (immune system...
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Our funding programs support basic, translational and clinical research from academia and industry.