The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2005Specific Inhibition of Nucleation of Alpha-synuclein Aggregation as a Therapeutic Strategy
There is considerable evidence that aggregates of the human brain protein alpha-synuclein are a primary cause of the loss of neurons in Parkinson's disease. We have tried to find out what initiates...
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Community Fast Track, 2005Use of NR2D-selective NMDA Receptor Modulators in the Treatment of PD
The frontline pharmacological treatment for Parkinson’s disease is associated with serious side effects, creating a need for new therapeutic strategies. Recent evidence suggests that selective...
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Specification, Patterning, and Maintenance of Midbrain Dopam, 2005Engineering Midbrain Dopamine Neurons by Forced Expression of a Novel Dopamine Cell Determinant in Pre-Clinical Model Embryonic Stem Cells
Understanding how the different cells of the brain are generated during embryonic development is one of the fundamental questions in biology. Recent studies have elucidated several key mechanisms...
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Clinical Discovery Awards, 2005Executive, ADL, and Cholinergic Functions in PD
Parkinson's disease is a disorder that is most known for motor impairments of tremor, slowness in moving, and loss of balance. Patients with Parkinson's disease also suffer from non-motor symptoms...
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Clinical Discovery Awards, 2005Ability to Slow Disease Progression and Safety and Tolerability of Green Tea Polyphenols in Early Parkinson’s Disease
Objective/Rationale:
Previous studies have shown that tea drinking is associated with a reduced of risk for Parkinson's disease (PD). Green tea polyphenols (GTPs), the major components of green tea... -
Clinical Discovery Awards, 2005Dysfunction of the Blood-Brain Barrier: The Cause of Parkinson's Disease
The causes of Parkinson's disease are still unclear. Genetic vulnerability and exposure to environmental neurotoxins are assumed to be contributors to nerve cell loss (neurodegeneration) in certain...
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Our funding programs support basic, translational and clinical research from academia and industry.