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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Accelerating the Translation of Parkinson's Disease Therapies, 2022
    Testing Small Molecules that Activate Removal of Cellular Debris for the Treatment of Parkinson’s Disease

    Study Rationale:
    People with Parkinson’s disease (PD) exhibit a diminished ability to remove cellular trash — including old and damaged molecules and organelles — from the brain. This impairment is...

  • Research Grant, 2022
    Development of PET Tracer for Imaging SV2C in Parkinson's Disease

    Study Rationale: Cells in the brain uses molecules such as dopamine, the neurotransmitter that is depleted in people with Parkinson’s disease (PD), to transmit signals from one to another. The...

  • Research Grant, 2022
    WATCH-PD Remote Digital Health Technology Extension: Planning Period

    Study Rationale: In the WATCH-PD study, we evaluated the use of wearable digital devices to monitor symptoms and quality of life in individuals with early, untreated Parkinson’s disease (PD). This...

  • Research Grant, 2022
    Identifying Bothersome Symptoms, Impacts of Disease and Relevance of WATCH-PD Digital Measures Over Time in Early Parkinson’s Disease

    Study Rationale: Parkinson’s disease (PD) is a devastating neurologic disease and current treatments are unable to prevent the worsening of symptoms. One problem in developing new therapies has been...

  • Research Grant, 2022
    Examining the Role of Cannabinoid Receptor 2 in Inflammatory Responses Triggered by Alpha-synuclein

    Study Rationale: There is growing interest in the anti-inflammatory properties of cannabis-related compounds as a potential therapy for Parkinson’s disease (PD). Cannabis acts on cannabinoid receptors...

  • Research Grant, 2022
    Development of a Radiolabeled Tracer for Detecting Insoluble Protein Aggregates in Parkinson’s Disease

    Study Rationale: Many neurodegenerative disorders are caused by a toxic buildup of insoluble protein aggregates.  In Parkinson’s disease (PD), accumulation of alpha-synuclein contributes to the death...

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