The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2010Symptoms and Side Effects of LRRK2 Mutation Carriers and Assessment of Factors Influencing LRRK2-related PD Expression
Objective/Rationale:
By incorporating our Spanish LRRK2 cohort with G2019S and R1441G mutations into the existing LRRK2 Cohort Consortium (L2CC) of people of Ashkenazi Jewish and North African Arab... -
MJFF Research Grant, 2010Development of Selective LRRK2 Inhibitors
Objective/Rationale:
LRRK2 kinase has been implicated as a potential therapeutic target for the treatment of Parkinson’s disease. The goal of our project is to make experimental drugs to test whether... -
LRRK2 Target Engagement Ligand, 2011Evaluating Novel Small Molecule Inhibitors of LRRK2 to Deliver PET Ligands
Objective/Rationale:
The exciting discovery of activating mutations in the LRRK2 kinase in familial PD patients, coupled with the emergence of kinase inhibitors as a new class of efficacious drugs... -
Rapid Response Innovation Awards, 2011Developing a Human Neural Model for Parkinson's Disease
Objective/Rationale:
Advances in the knowledge and treatment of Parkinson’s disease (PD) are limited by the inability to obtain, grow and study neural cells from the brains of living patients. Small... -
MJFF Research Grant, 2011Development and Test of a P25a Competitive Alpha-synuclein Aggregate Binding Assay and Test of Thioflavin-T as Competitor
Objective/Rationale:
Compounds targeting aggregated alpha-synuclein are high in demand as potential bio-imaging tools. We have previously developed an assay that measures the binding of the protein... -
MJFF Research Grant, 2011Just in Time Pre-clinical Resource for Evaluating Symptoms & Side Effects and/or Dyskinesia Treatments
Objective/Rationale:
There is a clear need for the development of novel treatments to better manage the symptoms of Parkinson’s disease. While current treatments address some of the motor symptoms of...
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Our funding programs support basic, translational and clinical research from academia and industry.