The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Circuit Dysfunction Underlying Motor and Sleep Deficits in a Progressive Preclinical Model of Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) begins decades before it compromises an individual’s ability to move about in the world and sleep through the night. Understanding how the dysfunction of...
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ASAP CRN Competitive Renewal Opportunity, 2024Parkinson5D: Deconstructing Disease Mechanisms Across Cells, Space and Progression
Study Rationale: Although thousands of DNA variants are linked to Parkinson’s disease (PD), their exact functions are unknown. These variants are in the “dark matter” of our genome and do not lead to...
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Cortical Pathophysiology of Parkinsonism
Study Rationale: Activity changes in nerve cells in the brain’s cerebral cortex are central to Parkinson’s disease (PD). However, which specific cell types are affected, and how and when their...
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ASAP CRN Competitive Renewal Opportunity, 2024Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
Study Rationale: Many people with Parkinson’s disease (PD) develop untreatable cognitive symptoms due to changes in the brain’s cerebral cortex. These symptoms, which include problems with attention...
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ASAP CRN Competitive Renewal Opportunity, 2024Activation of Transposable Elements as a Trigger of Neuroinflammation in Parkinson’s Disease
Study Rationale: Inflammation is a common event in neurodegenerative diseases such as Parkinson's disease (PD), although its source remains unclear. Many different factors can potentially trigger...
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ASAP CRN Competitive Renewal Opportunity, 2024Redefining the Pathophysiological Mechanisms of Parkinson’s Disease in the Context of Heterogeneous Neuronsl Subtypes in the Substantia Nigr
Study Rationale: The motor symptoms of Parkinson's disease (PD) result from the degeneration of dopamine-producing neurons in a brain area called the substantia nigra pars compacta (SNc). Recent...
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Our funding programs support basic, translational and clinical research from academia and industry.