The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Therapeutic Pipeline Program, 2017Pre-clinical Development of LBT-3627, a Potential Neuroprotective and Anti-inflammatory Therapy for Parkinson's Disease
Study Rationale:
Adaptive and innate immune responses play important roles in neuroinflammation and can be harnessed to improve outcomes in Parkinson's disease (PD). Daily administration of LBT-3627... -
Research Grant, 2016Characterization, Optimization and Validation of a Preformed Fibril Pre-clinical Model of Parkinson's Disease
Study Rationale:
New pre-clinical models have been developed to study the hypothesis that damaging forms of alpha-synuclein (protein involved in Parkinson's) spread across brain regions from a single... -
Research Grant, 2016Design and Identification of a LRRK2 Kinase Structural Surrogate
Study Rationale:
Due to the importance of the LRRK2 protein in Parkinson's disease (PD), many academic and industrial laboratories have attempted to solve the three-dimensional structure of the kinase...
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Research Grant, 2017Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin
Promising Outcomes of Original Grant:
Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the... -
Access to Data and Biospecimens, 2018Uric Acid as an Antioxidant Treatment for LRRK2-associated Inherited Parkinson's Disease
Objective/Rationale:
Uric acid is a chemical produced naturally in the human body. In this project, we aim to investigate whether uric acid is an antioxidant capable of reducing the risk of Parkinson's... -
Research Grant, 2018Does Mitochondrial Dysfunction in the Skin Predict That in the Brain?
Study Rationale:
Mitochondria -- the power generators of the cell -- do not function properly in Parkinson's disease (PD). This dysfunction, however, is not always present and can vary in its severity...

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Our funding programs support basic, translational and clinical research from academia and industry.