The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Mitochondrial Biomarkers Program, 2018Developing Precision Biomarkers of Parkinson's Disease
Study Rationale:
Leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD). Research studies have linked mutations (changes) in the LRRK2 gene to DNA... -
Research Grant, 2018The Interplay between Genetic and Environmental Mechanisms in Parkinson’s Disease
Study Rationale:
Genes implicated in Parkinson's disease (PD), such as alpha-synuclein, DJ-1 and LRRK2, strongly influence the effect of environmental toxins, such as pesticide rotenone know to cause... -
Research Grant, 2018Discovery of Microbiome Biomarkers for Parkinson's Disease
Study Rationale:
The gut microbiome -- a community of microorganisms living in the gastrointestinal tract -- influences the development of the nervous system, affects behavior and contributes to... -
Research Grant, 2018Examining GCase Activity in People with REM Sleep Behavior Disorder
Study Rationale:
Approximately 80 percent of people with REM sleep behavior disorder (RBD) will develop a neurological disorder such as Parkinson's disease (PD). GBA mutations are the most frequent... -
Research Grant, 2018Tracing Hallmarks of Parkinson's Disease in the Brain with a New Compound
Study Rationale:
Parkinson's disease (PD) is characterized by the presence of protein alpha-synuclein clumps in the brain. PD shares common features with other neurodegenerative diseases and because an... -
LRRK2 Biology Consortium, 2018Developing Cell-Based Tools for the Evaluation of LRRK2 Inhibitors
Promising Outcomes of Original Grant:
Mutations in the LRRK2 gene are a leading genetic cause of Parkinson's disease (PD) and cause dysfunction in the LRRK2 protein. We have previously demonstrated...

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Our funding programs support basic, translational and clinical research from academia and industry.