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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biomarkers, 2009
    High Resolution Diffusion Tensor Imaging in Parkinson's Disease and Parkinson Plus Syndromes

    Objective/Rationale
    An objective and valid trait and state biomarker of Parkinson’s disease will help therapeutic development by providing a measure to help confirm diagnosis (trait), and track...

  • Rapid Response Innovation Awards, 2009
    Possibility of Small Molecule Activation of PINK1 Kinase Activity

    Objective/Rationale
    Many genetic disorders are caused by the loss of a functional protein which protects cells from disease. These disorders are difficult to treat with drugs because most drugs block...

  • MJFF Research Grant, 2009
    Supplemental Biomarkers Study to Clinical Trial for CoQ10

    Objective/Rationale
    There is a critical need for biomarkers of Parkinson’s disease (PD), for accurate and earlier diagnosis, and for monitoring treatment effects. We are investigating two potential...

  • MJFF Research Grant, 2009
    Assessing Heart Rate Variability (HRV) in the Parkinson's Associated Risk Study (PARS) Cohort

    Objective/Rationale
    The objective of this study is to determine if HRV, which is reduced in PD, is significantly reduced in subjects with hyposmia (loss of smell) compared to subjects who are...

  • Rapid Response Innovation Awards, 2009
    Validating the Electrocardiogram as a Tool to Identify Pre-motor Parkinson's Disease

    Promising Outcomes of Original Grant:
    Our goal in the funded RRIA was to determine if a 5 minute EKG recordings in patients with a high probably of having pre-motor PD, i.e., individuals with...

  • Research Grant, 2009
    Biomarkers of Pioglitazone Effects in Parkinson's Disease (BioPEP)

    Objective/Rationale
    Pioglitazone is a medication used to treat diabetes that that has shown promise in laboratory studies for potentially slowing the progression of Parkinson’s disease (PD). The...

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