The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2022Creation and Testing of a Combined Cognitive Score in Parkinson Disease
Study Rationale: Many different tests of memory and thinking are given to people with Parkinson’s disease (PD), but it is not clear how to use or combine these test scores to best detect early...
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Novel PET Tracer Development Program, 2023Development of a PET Tracer for Imaging of Neuroinflammation in Parkinson’s Disease
Study Rationale: Neuroinflammation plays a key role in the degeneration of dopamine-producing neurons and is critical in the pathogenesis of Parkinson’s disease (PD). Positron Emission Tomography (PET...
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Biomarkers to Support Therapeutic Trials Program, 2023Blood Test for Stratifying People with Parkinson’s Disease based on Extracellular Vesicles Derived from Neurons
Study Rationale: Parkinson’s disease (PD) and other synucleinopathies are diagnosed based on symptoms and clinical testing. However, these tests can be inaccurate, and postmortem analysis reveals that...
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Spring 2022 RFP: Proof-of-Concept Testing of PD Therapeutics, 2022Preclinical Models and Therapies for the Gastrointestinal Symptoms of Parkinson’s Disease
Study Rationale: In addition to the well-recognized movement abnormalities associated with Parkinson’s disease (PD), gastrointestinal symptoms such as constipation, leaky gut and inflammation are also...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Inhibiting Programmed Cell Death to Reduce Axonal Degeneration and Brain Inflammation in Parkinson's Disease
Study Rationale: The degeneration of neuronal axons is an early pathological feature of Parkinson’s disease (PD) and an attractive target for therapeutic intervention. We have demonstrated that a...
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Research Grant, 2022Establishing a Parkinson’s Disease Registry in West Virginia
Study Rationale: The state of West Virginia has one of the nation’s highest rates of Parkinson’s disease (PD), a condition for which the causes are not well understood and there is no cure. In April...
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Our funding programs support basic, translational and clinical research from academia and industry.