The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biosample Use Program, 2020Single-molecule Detection of Oligomeric Synuclein in Body Fluids
Study Rationale:
Clumps, or aggregates, of the protein alpha-synuclein have been detected in spinal fluid of people with Parkinson’s disease, where its concentration shows potential to be a biomarker... -
Research Grant, 2020RT-QuIC Assay for Alpha-synuclein in Incidental Lewy Body Disease
Study Rationale:
In Parkinson's, the alpha-synuclein protein misfolds and aggregates into clumps, called Lewy bodies. When Lewy bodies are found in people without Parkinson’s, it can be diagnosed as... -
Research Grant, 2020GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease
Study Rationale:
Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have... -
Therapeutic Pipeline Program, 2019Identification of Novel Compounds that Improve Mitochondrial Quality Control
Study Rationale:
Dysfunction of mitochondria, the powerhouses of the cell, has been linked to degeneration in nerve cells in Parkinson’s disease. When mitochondria can’t function properly, cellular... -
Aligning Science Across Parkinson's, 2020Impaired Integration of Organelle Function in Parkinson’s Disease
Study Rationale:
Geneticists have made great progress in identifying gene mutations that either cause Parkinson’s or increase disease risk. The critical next step is to determine how some of these... -
, 2022Studying the Epidemiology of Parkinson’s Disease in Latin America: Learning from Underrepresented Populations
Study Rationale: Initial evidence has shown that the global distribution of Parkinson’s disease (PD) may vary; however, little is known about the prevalence of PD across large parts of the world. This...
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Our funding programs support basic, translational and clinical research from academia and industry.