The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2023A Phase I Retest Study of Imaging Tracer MODAG-005 in Parkinson’s Disease, Multiple System Atrophy and Healthy Volunteers
Study Rationale: In many neurodegenerative disorders, including Parkinson’s disease (PD) and (MSA), the protein alpha-synuclein is structurally altered and forms aggregates in the brain. These...
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Research Grant(Supplement) Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson’s Disease
Study Rationale: Most people with Parkinson’s disease (PD) develop voice and speech problems at some point during the course of the disease. Such problems, collectively known as the motor speech...
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Research Grant, 2023Leveraging Gene Expression Data to Redefine Parkinson’s Disease and the Pathways Driving Disease in Different Individuals
Study Rationale: People with Parkinson’s disease (PD) share some common problems, such as stiffness, slowness of movement and tremors. However, these symptoms vary in severity, and individuals often...
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Parkinson’s Pathway Molecular Data Analysis Program, 2023Characterization of Parkinson’s Disease Clinical Subtypes Using Multiple Immunologic and Genetic Markers
Study Rationale: Parkinson’s disease (PD) is an umbrella term that encompasses a highly heterogeneous domain of clinical manifestations, which makes the development of effective therapeutic strategies...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Developing Small Molecules to Enhance Autophagy and Clear Alpha-synuclein Aggregates as a Treatment for Parkinson’s Disease
Study Rationale: Autophagy is a process by which cells dispose of damaged or improperly functioning cell components. Recent evidence points at defects in autophagy as a feature of Parkinson’s disease...
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Accelerating the Translation of Parkinson's Disease Therapies, 2023Evaluating Polyamines as Biomarkers for Parkinson’s Disease
Study Rationale: One of genes associated with Parkinson’s disease (PD), ATP13A2, regulates the levels of polyamines in the lysosome, an acidic compartment of the cell. Polyamines are neuroprotective...
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Our funding programs support basic, translational and clinical research from academia and industry.