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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biosample Use Program, 2020
    Mass Spectrometric Analysis of Glucocerebrosidase Protein Levels and Spinal Fluid in People with Parkinson’s

    Study Rationale:
    Mutations in the glucocerebrosidase (GBA) gene are among the most important risk factors for developing Parkinson´s disease. GBA activity is reduced in cerebrospinal fluid (CSF) of...

  • Biosample Use Program, 2020
    Adaptive Immune Markers for Predicting Cognitive Decline in Parkinson’s Disease

    Study Rationale:    
    For reasons not well understood, people with Parkinson's disease are at risk for developing dementia, a decline in memory, thinking and/or language abilities severe enough to...

  • Research Grant, 2020
    Cytokine Production by Adaptive Immune Cells in Parkinson’s Disease: Response to Diverse Biological Stimuli

    Study Rationale:
    Many studies indicate a role for the adaptive immune system in Parkinson’s disease. Our study will produce proteins called cytokines that play a role in the immune response to...

  • Research Grant, 2020
    Targeted and Untargeted Mass Spectrometry-Based Proteome Investigation of Urine in Parkinson’s Disease

    Study Rationale:
    There is an urgent need for disease indicators — also known as biomarkers — in Parkinson’s disease to enable early diagnoses and treatment response monitoring. Urine is a promising...

  • Therapeutic Pipeline Program, 2020
    Photoreceptor-Directed Light Therapy in Parkinson’s Disease

    Study Rationale:    
    Non-motor symptoms including sleep disturbances are common and enormously impact quality of life in people with Parkinson’s disease (PD). Sleep disruption affects motor function...

  • Research Grant, 2020
    Investigating the Role of LRRK2 in Tau Pathogenesis

    Study Rationale:
    While most cases of Parkinson’s disease have no known genetic cause, a subset of Parkinson’s is caused by mutations in the leucine-rich repeat kinase 2 (LRRK2) gene. It is believed...

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