The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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T2T Validation - NOD2, 2025Inflammatory and Regulatory Functions of NOD2 in the Setting of Parkinson’s Disease
Study Rationale: NOD2 is a signaling protein which has been found to be more abundant and more active in brain tissues of patients with Parkinson’s disease. Certain changes in the sequence encoding...
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Research Grant, 2024SUPPLEMENT: MJFF Consortium on PRKN and PINK1
Study Rationale: Recessively inherited forms of Parkinson’s disease (PD) caused by mutations on both copies of the genes PRKN and PINK1 are unique in many aspects. Age at onset is mainly before the...
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Research Grant, 2024Virtual Screening and Biochemical Confirmation of Small Molecule Activators of ATP10B
Study Rationale: Disruption of lysosomal glucosylceramide (GluCer) homeostasis is a key risk factor in Parkinson’s disease. ATP10B, a lysosomal GluCer exporter, has been linked to Parkinson’s through...
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Therapeutic Pipeline Program, 2024Integrin CLOAKs as Novel Oral Therapeutics for Parkinson’s Disease
Study Rationale: Increased neuroinflammation promotes neuron injury and loss (neurodegeneration) and drives progression of Parkinson’s Disease (PD), suggesting that controlling neuroinflammation is an...
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Our funding programs support basic, translational and clinical research from academia and industry.