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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2011
    Identifying Markers of PD Onset and Progression in a Prospective Cohort of Patients and ASymptoms & Side Effects Carriers of LRRK2 Mutations

    Objective/Rationale:
    LRRK2 mutations constitute one of the most common genetic risk factors for PD. The prospective follow-up of PD patients and aSymptoms & Side Effects carriers of LRRK2 mutations...

  • Defining Cognitive Phenotypes of Parkinson’s Disease, 2011
    Predicting Cognitive Profiles in Parkinson's Disease: A Multimodal Approach

    Objective/Rationale:
    Our proposal aims to determine the optimum combination of techniques to detect rate of cognitive decline in people with newly diagnosed Parkinson’s disease (PD). We will apply...

  • Resource: Utilizing DATATOP Biospecimens, 2011
    Validation of Alpha-synuclein Oligomers as Biomarker for Parkinson’s Disease

    Objective/Rationale:
    We have reported recently higher levels of α-synuclein oligomers species in cerebral spinal fluid (CSF) from patients clinically diagnosed with Parkinson’s disease (PD) versus...

  • Resource: Utilizing DATATOP Biospecimens, 2011
    C-type Natriuretic Peptide (CNP): A Putative Biomarker of Neuronal Damage in Parkinson's Disease

    Objective/Rationale:
    CNP is a peptide produced by brain tissues where it acts to promote growth of nerve cells and their connections. Recent research in healthy humans has identified high...

  • Rapid Response Innovation Awards, 2011
    Direct Reprogramming of Cells into Dopamine Neurons

    Objective/Rationale: 
    The availability of dopaminergic neurons for in-depth study or therapeutic replacement approaches has traditionally been limited. We aim to reprogram cells into dopaminergic...

  • Rapid Response Innovation Awards, 2011
    Whole Exome Sequencing in an Amish Parkinson's Disease Pedigree

    Objective/Rationale: 
    Although there is strong evidence to suggest genetics plays a role in Parkinson’s disease, the majority of the genes involved in Parkinson’s disease remain unidentified. We...

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