The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Motor Proteins as Novel Drug Targets of Disease-modifying Treatments for Parkinson’s Disease
Objective/Rationale:
More and more research suggests that part of the cellular quality control mechanism, which degrades abnormal proteins or damaged parts of the cell, is defective in Parkinson’s... -
Research Grant, 2014Probing Nurr1 Expression in Parkinson’s Disease
Objective/Rationale:
Impaired function of the hormone receptor Nurr1 might contribute to the pathogenesis of Parkinson’s disease (PD) and is an active target for novel therapeutics. Previous studies... -
Rapid Response Innovation Awards, 2014Potential of Cell-permeable Parkin Proteins as a Treatment for Parkinson’s Disease
Objective/Rationale:
Parkin is an enzyme that protects cells, including neurons, from damage. Mutations in parkin can lead to loss of neurons and contribute to Parkinson’s disease (PD). We plan to... -
Research Grant, 2014Selective mGluR3 Positive Allosteric Modulators as Neuroprotective Agents for Parkinson's Disease
Objective/Rationale:
mGluR3 is a protein and target for neuroprotection. We have recently demonstrated that selective mGluR3 positive allosteric modulators (PAMs) mimic neuroprotective... -
Parkin Therapeutic Development, 2014Identification of Small Molecules that Stabilize Parkin in an Active Conformation
Objective/Rationale:
Parkin is a protein linked to hereditary, young-onset Parkinson’s disease (PD) through a series of genetic mutations. Its formal role in PD is not fully understood, but its... -
Research Grant, 2014Parkin-mediated Mitigation of Neurodegeneration Induced by Overexpression of Alpha-synuclein Using AAV Vectors
Objective/Rationale:
Mutations in the gene for the protein parkin gene can cause Parkinson’s disease (PD), and parkin is involved in the breakdown of damaged proteins. This makes parkin an important...
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Our funding programs support basic, translational and clinical research from academia and industry.