The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2014Directed Evolution of Bacteria for Recombinant Expression and Purification of LRRK2
Study Rationale:
Mutations in the gene that encodes the LRRK2 protein are frequent causes of Parkinson’s disease (PD). An obstacle to understanding how these mutations lead to PD is... -
Rapid Response Innovation Awards, 2014Defining the Contribution of Neuroinflammation to Parkinson's Disease
Study Rationale:
Over-activation of brain immune cells, called microglia, is associated with the degeneration that occurs in Parkinson’s disease. This suggests that brain... -
Therapeutic Pipeline Program, 2014Augmenting Treatment Effects of Voice Therapy in Parkinson’s Disease
Study Rationale:
Speech and voice disorders are common in people with Parkinson’s disease (PD) and adversely affect their communication and quality of life. Presently, Lee Silverman... -
Therapeutic Pipeline Program, 2014Prevention of Levodopa-induced Dyskinesia by Transcranial Static Magnetic Field Stimulation
Study Rationale:
A major challenge in Parkinson’s treatment is the management of levodopa-induced dyskinesias. A promising approach is offered by non-invasive neuromodulation techniques. We recently... -
Research Grant, 2014Predicting the Efficacious Dose of the Selective 5-HT1A Agonist NLX-112
Study Rationale:
The dopamine precursor levodopa is the gold-standard treatment for Parkinson’s disease. However, as PD progresses, serotonin neurons increasingly convert levodopa to... -
Rapid Response Innovation Awards, 2014Identifying and Characterizing Genetic Causes of REM Sleep Behavior Disorder and Parkinson’s Disease
Study Rationale:
During the rapid eye movement (REM) phase of sleep, when we dream, our voluntary muscles are paralyzed so that we would not act out our dreams. In REM sleep behavior...

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Our funding programs support basic, translational and clinical research from academia and industry.