The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2021Gut Inflammation and Microbial Imbalance in Parkinson’s Disease
Study Rationale: Studies show that the intestinal environment can affect the activity of the nervous system, and inflammation in the gut could contribute to the brain changes associated with Parkinson...
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Outcome Measures, 2021Development of a Method for Assessing the Effectiveness of Alpha-synuclein Immunotherapy
Study Rationale: Parkinson’s disease (PD) is characterized by the buildup of misfolded forms of alpha-synuclein. A vaccine designed to target this abnormal protein has demonstrated safety...
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Therapeutic Pipeline Program, 2021Development of an Anti-inflammatory Drug for the Treatment of Parkinson’s Disease
Study Rationale: Persistent activation of the immune cells that reside in the brain leads to a state of chronic inflammation that contributes to the degeneration of neurons in Parkinson’s disease (PD)...
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Research Grant, 2021Preclinical Testing of a Novel Tracer for Imaging Alpha-synuclein Aggregates
Study Rationale: In Parkinson's disease (PD), the protein alpha-synuclein is structurally altered such that clumps of alpha-synuclein accumulate in the brain. These aggregates impair the function of...
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Target Advancement Program, 2021Exploring How a Chemical Produced by Intestinal Microbes Contributes to the Pathology and Progression of Parkinson's Disease
Study Rationale: Imbalances in the bacteria that inhabit the gut have been linked to the onset and progression of Parkinson’s disease (PD). However, the mechanisms by which an altered microbiome can...
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Research Grant, 2021Hidden Sorrows of Covid-19: Impact of Stress on Parkinson’s Disease Progression
Study Rationale: People living with Parkinson’s disease (PD) are very sensitive to stress, which worsens motor symptoms (such as tremor) and leads to anxiety and depression. Studies in animals suggest...
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Our funding programs support basic, translational and clinical research from academia and industry.