The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020Targeting of the Raphe-Cortical Pathway to Reduce Levodopa-Induced Psychosis
Study Rationale:
Parkinson’s disease is best known as a movement disorder, yet non-motor symptoms such as anxiety, depression and psychosis afflict over 50 percent of patients and severely impact... -
Research Grant, 2020More Than Pretty Pictures: Ion Imaging of Lipid Content and Flux Kinetics in Models of Parkinson’s Disease
Study Rationale:
Glycosphingolipids are natural cellular fats. They are components of cellular membranes that fulfill multiple functional roles, from cell structure and transport to signaling. The... -
Research Grant, 2020Parkinson’s Disease with Mild Cognitive Impairment Treated with a Nicotinic Agonist Drug
Study Rationale:
Parkinson’s disease with mild cognitive impairment (PD-MCI) is common, has important clinical consequences, and there is currently no treatment available. The underlying pathology of... -
Research Grant, 2020Detecting Colonic Alpha-synuclein with an Antibody Specific for Disease-associated Forms as a Biomarker of Parkinson’s Disease
Study Rationale:
Despite several published studies using different anti-alpha-synuclein antibodies, to date no lab-based methods have been able to reliably identify Parkinson’s disease (PD) cases from... -
Research Grant Supplement, 2020LIMP-2 as a Scaffolding Protein to Characterize PD-Associated GCase Variants
Promising Outcomes of Original Grant:
Our original grant focused on determining the structure of the complex formed by the Parkinson’s-associated protein beta-gluccocerebrosidase (GCase) and its... -
Research Grant, 2020Targeted and Untargeted Mass Spectrometry-Based Proteome Investigation of Urine in Parkinson’s Disease
Study Rationale:
There is an urgent need for disease indicators — also known as biomarkers — in Parkinson’s disease to enable early diagnoses and treatment response monitoring. Urine is a promising...
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Our funding programs support basic, translational and clinical research from academia and industry.