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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    Assessing Target Engagement for Terazosin

    Study Rationale:    
    Patients with Parkinson’s disease (PD) do not produce enough of a compound called ATP. If a person does not make enough ATP, the cells in the body can die. This is very important...

  • Research Grant, 2020
    Safety and Tolerability of NLX-112 in People with Parkinson’s

    Study Rationale:
    Motor symptoms of Parkinson’s disease are caused by a lack of brain neurons that carry a neurotransmitter called dopamine, and are commonly treated with levodopa. However, after...

  • Biosample Use Program, 2020
    Mass Spectrometric Analysis of Glucocerebrosidase Protein Levels and Spinal Fluid in People with Parkinson’s

    Study Rationale:
    Mutations in the glucocerebrosidase (GBA) gene are among the most important risk factors for developing Parkinson´s disease. GBA activity is reduced in cerebrospinal fluid (CSF) of...

  • Biosample Use Program, 2020
    Identification of Autoantibodies in People at Risk of Developing Parkinson’s Disease Using Microarrays

    Study Rationale:    
    Autoantibodies are antibodies that mistakenly target and react with a person's own tissues or organs. Autoantibodies can be detected many years before symptoms develop in many...

  • Aligning Science Across Parkinson's, 2020
    In Vivo Approach to Elucidate the Pathobiology of Parkinson’s-associated Genes Using Human Diseased Neurons
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    Study Rationale:
    Several genes are known to be associated with Parkinson’s disease, although how they impact the disease process is not fully understood. Here we will use stem cells from patients in...

  • Aligning Science Across Parkinson's, 2020
    Senescence in Parkinson’s Disease and Related Disorders
    ASAP logo

    Study Rationale:
    While aging is the greatest risk factor for development of Parkinson’s disease (PD), how aging promotes PD is not fully understood. Examining the role of cellular senescence...

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