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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Freezing of Gait Program, 2025
    AID-FOG: Artificial Intelligence-driven Freezing of Gait Detection in the Home

    Study Rationale: Freezing of gait (FOG) is a symptom that causes many people with Parkinson’s disease (PD) to suddenly lose their ability to take a step while walking, creating a high risk for falling...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Assessing the Aggregation of Alpha-synuclein Across Aging, Alzheimer’s Disease and Dementia with Lewy Bodies

    Study Rationale: Forms of alpha-synuclein, the protein that aggregates in Parkinson’s disease (PD), can be detected in cerebrospinal fluid (CSF) by seed amplification assays (SAA). These highly...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Testing Biofluid Samples from the Arizona Study of Aging and Neurodegenerative Disorders for Alpha-synuclein and Biomarkers of Alzheimer’s Disease

    Study Rationale: The Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) has amassed a comprehensive collection of samples and longitudinal clinicopathological data. In this project, we...

  • Research Grant, 2025
    Evaluation of Novel PET Probes for Alpha-synuclein Imaging

    Study Rationale: Aggregation of the protein alpha-synuclein into fibrils in Lewy bodies and Lewy neurites is the key pathological feature of Parkinson's disease (PD) and related synucleinopathies...

  • Research Grant, 2025
    Assessment of Artificial Intelligence (AI) and Blood-Brain Barrier Technology

    Study Rationale: Companies are currently using artificial intelligence (AI) to design and develop new drugs and developing new ways to get drugs across the protective blood-brain barrier (BBB) and...

  • , 2022
    Uncovering Proteomic Alterations in Parkinson’s Disease Using Patient-specific iPSC-derived Brain Cells

    Study Rationale: Transgenic small models have been used as gold standard to study human brain diseases, but it is unclear how conclusive and faithfully these models reflect pathophysiological...

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