The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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[RFA] Use of PD Biosamples - Spring 2020, 2024Neurotoxic Inflammatory Metabolites as Biomarkers of Disease Progression in Parkinson’s Disease
Study Rationale: Individuals with Parkinson’s disease (PD) have inflammation in the brain, cerebrospinal fluid and the blood. We think that inflammation drives the worsening of PD because it increases...
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Research Grant, 2024Chronos-PD Pilot: Analyzing Plasma from Donors Who Develop Parkinson’s Disease Later in Life
Study Rationale: Our current molecular understanding of Parkinson’s disease (PD) is based on the clinical phase of the disease. However, because PD is a progressive disease, by the time the disorder...
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Parkinson’s Disease Therapeutics Pipeline Program, 2024Preclinical Development of a Novel Therapeutic for Parkinson’s Disease
Study Rationale: Inflammation in the brain (neuroinflammation) is a key feature of Parkinson’s disease (PD), and signaling molecules called prostaglandins play a pivotal role in controlling chronic...
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Research Grant, 2024(SUPPLEMENT) Cataloguing Proteomic Differences in LRRK2-Associated Parkinsonism With and Without Evidence of Pathologic Neuronal Alpha-synuclein
Study Rationale: Alpha-synuclein is a protein found throughout the brain and body. In most people with Parkinson’s disease (PD), an accumulation of abnormal alpha-synuclein is thought to contribute to...
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Biomarkers to Support Therapeutic Trials Program, 2024Using Detection of Apoptosing Retinal Cells to Predict Disease Activity in Parkinson’s Disease
Study Rationale: In preclinical models, detection of apoptosing retinal cells (DARC) allows identification of cells in the eye that are under stress and at risk of damage from Parkinson’s disease (PD)...
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Research Grant, 2024Developing A Resource for Exploring the Molecular Markers of Parkinson’s Disease
Study Rationale: Our understanding of the genetic, immunological and molecular determinants of Parkinson’s disease (PD) has advanced significantly over the past decade. Using this extensive body of...
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Our funding programs support basic, translational and clinical research from academia and industry.