The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Fast Track, 2001PET Neuroimaging Study of the Brain Serotonin Transporter in Parkinson's Disease: Relationship to Clinical Depression
Approximately 40% of patients with Parkinson's disease (PD) suffer from depression, which in many cases is more disabling than the impairment of motor function. Since the original discovery by Oleh...
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Repositioning Drugs for PD, 2012Amitriptyline as a Dopamine Neuroprotective Therapy
Objective/Rationale:
The project proposes to repurpose the tricyclic antidepressant medication, amitriptyline (AMI), as a disease-modifying therapy for Parkinson’s disease (PD). AMI is an FDA-approved... -
ASAP CRN 2025 RFA Scientific Track, 2026Defining Functional Heterogeneity Within the Subthalamic Area and Its Relevance for Psychiatric Symptoms of PD
Study Rationale:
Anxiety, depression, reduced motivation, and impaired cognition are common symptoms in Parkinson’s disease (PD), often occurring early in its course, before...
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Rapid Response Innovation Awards, 2008Effects of noradrenergic or serotoninergic system lesions combined with NS lesions on rodent models of 'non-motor'-like symptoms
Objective/Rationale:
Parkinson’s disease is widely attributed to neuropathy of dopaminergic neurones in the nigrostriatal (NS) pathway. Degeneration of noradrenergic and serotonergic neurones in the... -
Clinical Intervention Awards, 2009MASTER PD: Magnetic Stimulation for the Treatment of Motor and Mood Symptoms of Parkinson's Disease: A Four-Center, Sham-Controlled, Parallel Group Study
Objective/Rationale:
To determine the efficacy and duration of benefit of noninvasive brain stimulation with repetitive transcranial magnetic stimulation (rTMS) to modulate brain activity in order to... -
Diversity, Equity and Inclusivity in Parkinson's research, 2022Engaging the LGBTQIA+ Community, Caregivers and Care Providers in Research on Living with Parkinson’s Disease
Study Rationale: Four million LGBTQIA+ adults age 50 and above live in the United States. We know very little about the needs of those in the LGBTQIA+ community who are living with Parkinson’s disease...
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Our funding programs support basic, translational and clinical research from academia and industry.