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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • LRRK2 Biology Consortium, 2017
    Developing a LRRK2-deactivating Vitamin for the Treatment of Parkinson’s Disease

    Study Rationale:
    One of the most common inherited causes of Parkinson’s disease (PD) is defect in the LRRK2 protein caused by changes, or mutations, of the LRRK2 gene. These LRRK2 mutations cause the...

  • Research Grant, 2017
    Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease

    Study Rationale:
    It is well known that the alpha-synuclein protein clumps in the cells of people with Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in...

  • Computational Science, 2017
    Using Mathematical Tools to Explain the Variability in Parkinson’s Disease Symptoms and Progression

    Study Rationale: 
    Parkinson’s disease (PD) symptoms and progression vary greatly, making each Parkinson’s experience unique. The goal of this study is to winnow out the most relevant factors...

  • LRRK2 Biology Consortium, 2017
    Describing the Structure and Function of LRRK2

    Study Rationale:
    Although leucine-rich repeat kinase 2 (LRRK2) is the greatest known genetic contributor to Parkinson's disease (PD), little is known about its structure and function. To better...

  • Research Grant, 2017
    Using Neural Cells to Test New Drugs that Activate PINK1 and Parkin

    Promising Outcomes of Original Grant:
    Even though most people with Parkinson's disease (PD) do not have a genetic mutation -- a change in their DNA -- that causes the disease, genes can influence the...

  • Research Grant, 2017
    Radioactive Molecules for Detection of Alpha-synuclein and Amyloid-beta in the Brain

    Study Rationale:
    We will develop radioactive alpha-synuclein and beta-amyloid tracers -- molecules that allow researchers and clinicians to detect these two proteins in the brain using imaging...

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