The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2023Measuring Quality of Life in People with Parkinson’s Disease: State of the Art and Areas for Development
Study Rationale: Scales to measure quality of life are important tools for research. However, it is unclear whether currently available scales for measuring quality of life take into account the...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Validation of KLK6 as a New Therapeutic Target for Parkinson’s Disease
Study Rationale: Alpha-synuclein is the main protein that aggregates and forms Lewy bodies, the hallmark histological characteristics of Parkinson disease (PD). Multiple experimental studies suggest...
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Novel PET Tracer Development Program, 2023Monitoring Glucocerebrosidase Engagement in Parkinson’s Disease
Study Rationale: Glucocerebrosidase is an enzyme that is essential for maintaining healthy lipid metabolism throughout the human body. In Parkinson’s disease (PD), the efficiency of this protein is...
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Research Grant, 2023Enhancing Access to Meaningful Data: Nebraska Parkinson’s Disease Registry
Study Rationale: Nebraska’s Parkinson’s Disease Registry (NPDR) will roll out a new electronic data collection system, enforce state statutes requiring that physicians participate in reporting...
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Research Grant, 2023Exploiting a Novel Mechanism for Gene Regulation to Develop Innovative, Targeted Therapies for Parkinson’s Disease
Study Rationale: Neurodegenerative disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD) are associated with a variety of disease-causing mutations and genetic variants. In addition...
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Accelerating the Translation of Parkinson's Disease Therapies, 2023Development of Small Molecule Activators of Nurr1 as Potential Therapeutics for Parkinson's Disease
Study Rationale: Parkonson’s disease (PD) is characterized by neuroinflammation and the death of dopamine-producing neurons. Nurr1 is a protein that regulates the activity of genes to reduce...
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Our funding programs support basic, translational and clinical research from academia and industry.